SIGLEC6 抗体 (Internal Region)
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Quick Overview for SIGLEC6 抗体 (Internal Region) (ABIN499145)
抗原
See all SIGLEC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-KWMKYGYTSS K
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特异性
- This antibody is expected to recognize all reported isoforms (NP_001236.4, NP_942142.3, NP_942143.3).
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_001236.4, NP_942142.3 and NP_942143.3. Genename: SIGLEC6
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anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 27-347) antibody
SIGLEC6 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3C11C12G1 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) antibodySIGLEC6 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 371-453) antibodySIGLEC6 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 2G6 unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 1-437) antibodySIGLEC6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 76-269) antibodySIGLEC6 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 381-412), (C-Term) antibodySIGLEC6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (N-Term) antibodySIGLEC6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (C-Term) antibodySIGLEC6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (Internal Region) antibodyVerified SIGLEC6 适用: 人 ELISA, WB 宿主: 山羊 Polyclonal unconjugated
anti-Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6) (AA 1-437) antibodySIGLEC6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Peptide ELISA: Limit Dilution: 1/16000. Western blot: 0.5-1.5 μg/mL. This antibody detects bands at approx. 60 kDa and 30 kDa in HumanPlacenta lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SIGLEC6 (Sialic Acid Binding Ig-Like Lectin 6 (SIGLEC6))
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别名
- CD327 / SIGLEC6
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背景
- SIGLEC6 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells by binding to alpha2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC6, which interacts with LEP, is expressed at high levels in placenta (cyto-and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. It contains 1 copy of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in downmodulation of cellular responses. The phosphorylated ITIM motif binds to the SH2 domain of PTPN6/SHP-1. The gene for SIGLEC6 belongs to the immunoglobulin superfamily.Synonyms: CD33 antigen-like 1, CD33L, CD33L1, CDw327, OB-BP1, OBBP1, Obesity-binding protein 1, Sialic acid-binding Ig-like lectin 6, Siglec-6
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基因ID
- 946
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NCBI登录号
- NP_001236
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UniProt
- O43699
抗原
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