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NCR3 抗体

NCR3 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499098
发货至: 中国
  • 抗原 See all NCR3 抗体
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    适用
    • 51
    • 15
    • 4
    • 3
    人, 大鼠
    宿主
    • 44
    • 9
    克隆类型
    • 42
    • 11
    多克隆
    标记
    • 27
    • 4
    • 3
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This NCR3 antibody is un-conjugated
    应用范围
    • 26
    • 21
    • 20
    • 8
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    特异性
    This detects endogenous levels of NKp30 protein.
    交叉反应 (详细)
    Species reactivity (tested):Human and Rat.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product NCR3 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
    别名
    CD337 (NCR3 产品)
    别名
    MGC133750 antibody, 1C7 antibody, CD337 antibody, LY117 antibody, MALS antibody, NKp30 antibody, Nkp30 antibody, natural cytotoxicity triggering receptor 3 antibody, NCR3 antibody, Ncr3 antibody
    背景
    The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on IL-2 activated NK cells and NK cell lines as well as some in vitro activated γ/δ T cells. NKp30 enhances NK cell triggering and cytolysis of tumor targets and other target cells deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRζ. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.Synonyms: 1C7, LY117, NCR3, NKp30, Natural cytotoxicity triggering receptor 3
    分子量
    approx. 30 kDa
    基因ID
    259197
    NCBI登录号
    NP_667341
    UniProt
    O14931
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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