NCR3 抗体
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北京 101111
Quick Overview for NCR3 抗体 (ABIN499098)
抗原
See all NCR3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This detects endogenous levels of NKp30 protein.
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交叉反应 (详细)
- Species reactivity (tested):Human and Rat.
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纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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应用备注
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))
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别名
- CD337
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背景
- The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on IL-2 activated NK cells and NK cell lines as well as some in vitro activated γ/δ T cells. NKp30 enhances NK cell triggering and cytolysis of tumor targets and other target cells deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRζ. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.Synonyms: 1C7, LY117, NCR3, NKp30, Natural cytotoxicity triggering receptor 3
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分子量
- approx. 30 kDa
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基因ID
- 259197
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NCBI登录号
- NP_667341
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UniProt
- O14931
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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