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MDFI 抗体

MDFI 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499093
发货至: 中国
  • 抗原 See all MDFI 抗体
    MDFI (MyoD Family Inhibitor (MDFI))
    适用
    • 34
    • 10
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 31
    • 2
    • 2
    克隆类型
    • 34
    • 1
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MDFI antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 12
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of MDFI protein. (region surrounding Pro134)
    交叉反应 (详细)
    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product MDFI Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MDFI (MyoD Family Inhibitor (MDFI))
    别名
    MDFI (MDFI 产品)
    别名
    MDFI antibody, I-MF antibody, I-mfa antibody, I-mf antibody, RGD1560271 antibody, MyoD family inhibitor antibody, MDFI antibody, Mdfi antibody
    背景
    MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.Synonyms: MyoD family inhibitor
    分子量
    approx. 25 kDa
    基因ID
    4188
    NCBI登录号
    NP_005577
    UniProt
    Q99750
    途径
    Maintenance of Protein Location
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