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MDFI 抗体

This 兔 多克隆 antibody specifically detects MDFI in WB. It exhibits reactivity toward 人 和 小鼠.
产品编号 ABIN499093
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MDFI 抗体 (ABIN499093)

抗原

See all MDFI 抗体
MDFI (MyoD Family Inhibitor (MDFI))

适用

  • 34
  • 11
  • 6
  • 1
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  • 1
人, 小鼠

宿主

  • 31
  • 2
  • 2

克隆类型

  • 34
  • 1
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This MDFI antibody is un-conjugated

应用范围

  • 13
  • 13
  • 11
  • 11
  • 3
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of MDFI protein. (region surrounding Pro134)

    交叉反应 (详细)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % pure by SDS-PAGE
  • 应用备注

    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MDFI (MyoD Family Inhibitor (MDFI))

    别名

    MDFI

    背景

    MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation.Synonyms: MyoD family inhibitor

    分子量

    approx. 25 kDa

    基因ID

    4188

    NCBI登录号

    NP_005577

    UniProt

    Q99750

    途径

    Maintenance of Protein Location
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