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HOXB2 抗体

HOXB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499088
发货至: 中国
  • 抗原 See all HOXB2 抗体
    HOXB2 (Homeobox B2 (HOXB2))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This HOXB2 antibody is un-conjugated
    应用范围
    • 13
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    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of HoxB2 protein. (region surrounding Pro67)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product HOXB2 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    HOXB2 (Homeobox B2 (HOXB2))
    别名
    HOXB2 / HOX2H (HOXB2 产品)
    别名
    hox2 antibody, hox2h antibody, hox-2.8 antibody, Hoxb-2 antibody, Z-151 antibody, hoxb2 antibody, hm:zehn0229 antibody, HOX2 antibody, HOX2H antibody, Hox-2.8 antibody, K8 antibody, AI894218 antibody, Hoxbes2 antibody, homeobox B2 antibody, homeobox B2a antibody, homeobox protein Hox-B2 antibody, HOXB2 antibody, hoxb2 antibody, hoxb2a antibody, LOC733446 antibody, Hoxb2 antibody
    背景
    Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.Synonyms: Homeobox protein Hox-B2, Hox-2.8, Hox-2H, K8
    分子量
    approx. 38 kDa
    基因ID
    3212
    NCBI登录号
    NP_002136
    UniProt
    P14652
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