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HOXB2 抗体

This anti-HOXB2 antibody is a 兔 多克隆 antibody detecting HOXB2 in WB. Suitable for 人.
产品编号 ABIN499088
发货至: 中国

Quick Overview for HOXB2 抗体 (ABIN499088)

抗原

See all HOXB2 抗体
HOXB2 (Homeobox B2 (HOXB2))

适用

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宿主

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克隆类型

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多克隆

标记

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This HOXB2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of HoxB2 protein. (region surrounding Pro67)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % (by SDS-PAGE)
  • 应用备注

    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    HOXB2 (Homeobox B2 (HOXB2))

    别名

    HOXB2 / HOX2H

    背景

    Hox genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene HoxB1 is critical to hindbrain development and has phenotypic features frequently observed in autism. Analysis of expression and targeted disruption of HoxB1 demonstrates that it is also essential for patterning progenitor cells along the entire DV axis of rhombomere 4 (r4). HoxB1 maintains this function by acting very early during hindbrain neurogenesis to specify effectors of the Sonic hedgehog and Mash1 signaling pathways. HoxB2 is a homeodomain protein important in neural development that is also expressed during erythropoiesis, hindbrain development and normal human adult lung development. HoxB2 may modulate the amount of gamma-globin mRNA expressed during development and differentiation. In addition, HoxB2 plays an important role in the patterning of hindbrain and pharyngeal arches in the zebrafish.Synonyms: Homeobox protein Hox-B2, Hox-2.8, Hox-2H, K8

    分子量

    approx. 38 kDa

    基因ID

    3212

    NCBI登录号

    NP_002136

    UniProt

    P14652
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