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HFE 抗体

HFE 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN499087
发货至: 中国
  • 抗原 See all HFE 抗体
    HFE (Hemochromatosis (HFE))
    适用
    • 47
    • 9
    • 8
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 42
    • 6
    克隆类型
    • 44
    • 4
    多克隆
    标记
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HFE antibody is un-conjugated
    应用范围
    • 42
    • 20
    • 15
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of HLA-H protein. (region surrounding Ile104)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product HFE Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    HFE (Hemochromatosis (HFE))
    别名
    HFE / HLAH (HFE 产品)
    别名
    HFE1 antibody, HH antibody, HLA-H antibody, MVCD7 antibody, TFQTL2 antibody, MR2 antibody, hemochromatosis antibody, HFE antibody, Hfe antibody
    背景
    The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.Synonyms: Hereditary hemochromatosis protein
    分子量
    approx. 40 kDa
    基因ID
    3077
    NCBI登录号
    NP_000401
    UniProt
    Q30201
    途径
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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