AGFG2 抗体
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北京 101111
Quick Overview for AGFG2 抗体 (ABIN499086)
抗原
See all AGFG2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Rabr protein. (region surrounding Val131)
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交叉反应 (详细)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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应用备注
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AGFG2 (ArfGAP with FG Repeats 2 (AGFG2))
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别名
- AGFG2 / HRBL
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背景
- Rabr, also known as AGFG2 (Arf-GAP domain and FG repeats-containing protein 2), is a 481 amino acid member of the HIV-1 REV binding protein (HRB) family and has one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. Rabr shares 46 % identity with Rab. Both Rab and Rabr contain a zinc finger region near the N terminus, several phe-gly (FG) motifs, which is characteristic of nucleoporin-like proteins, and four NPF motifs located in the C-terminal region. Rabr interacts with Eps15 homology (EH) domains and plays a role in the REV export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs.Synonyms: Arf-GAP domain and FG repeats-containing protein 2, HIV-1 Rev-binding protein-like protein, RABR, Rev/Rex activation domain-binding protein related
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分子量
- approx. 49 kDa
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基因ID
- 3268
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NCBI登录号
- NP_006067
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UniProt
- O95081
抗原
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