GRAP2 抗体
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北京 101111
Quick Overview for GRAP2 抗体 (ABIN499081)
抗原
See all GRAP2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GRAP2 protein. (region surrounding asn158)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % pure by SDS-PAGE
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anti-GRB2-Related Adaptor Protein 2 (GRAP2) (AA 226-315) antibody
GRAP2 适用: 人 WB, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 1G12 unconjugated
anti-GRB2-Related Adaptor Protein 2 (GRAP2) (AA 1-330) antibodyGRAP2 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Related Adaptor Protein 2 (GRAP2) (AA 1-330) antibodyGRAP2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Related Adaptor Protein 2 (GRAP2) (C-Term) antibodyVerified GRAP2 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-GRB2-Related Adaptor Protein 2 (GRAP2) antibodyGRAP2 适用: 人 WB, IP, ICFC 宿主: 小鼠 Monoclonal UW40 unconjugated
anti-GRB2-Related Adaptor Protein 2 (GRAP2) (AA 20-262) antibodyGRAP2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Related Adaptor Protein 2 (GRAP2) antibody (PE)GRAP2 适用: 人 ICFC 宿主: 小鼠 Monoclonal UW40 PE
anti-GRB2-Related Adaptor Protein 2 (GRAP2) antibody (APC)GRAP2 适用: 人 ICFC 宿主: 小鼠 Monoclonal UW40 APC
anti-GRB2-Related Adaptor Protein 2 (GRAP2) antibodyGRAP2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GRB2-Related Adaptor Protein 2 (GRAP2) (AA 1-330) antibodyGRAP2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- GRAP2 (GRB2-Related Adaptor Protein 2 (GRAP2))
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别名
- GRAP2
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背景
- In general, it exists in association with catalytic domains, as in the nonreceptor protein-tyrosine kinases and phospholipase C-γ, within structural proteins, such as spectrin or myosin, and in small adapter proteins, such as Crk and GRB2. SH3 domains are often accompanied by SH2 domains of 100 amino acids that bind to tyrosine-phosphorylated regions of target proteins, frequently linking activated growth factors to putative signal transduction proteins. Deletion or mutation of SH3 domains generally activates the transforming potential of nonreceptor tyrosine kinases, suggesting that SH3 mediates negative regulation of an intrinsic transforming activity. Gads is an adapter proteins that contains both SH2 and SH3 domains. Gads binds to tyrosine-phosphorylated proteins, such as Shc, and functions to couple these proteins to downstream effectors.Synonyms: Adapter protein GRID, GADS, GRB-2-like protein, GRB2-related adapter protein 2, GRB2L, GRBLG, GRBX, GRID, Grf-40, Grf40 adapter protein, Growth factor receptor-binding protein, Hematopoietic cell-associated adapter protein GrpL, SH3-SH2-SH3 adapter Mona
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分子量
- approx. 38 kDa
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基因ID
- 9402
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NCBI登录号
- NP_004801
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UniProt
- O75791
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
抗原
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