GGH 抗体
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北京 101111
Quick Overview for GGH 抗体 (ABIN499075)
抗原
See all GGH 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GGH protein. (region surrounding Lys287)
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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应用备注
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- GGH (gamma-Glutamyl Hydrolase (Conjugase, Folylpolygammaglutamyl Hydrolase) (GGH))
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别名
- gamma-Glutamyl Hydrolase / GGH
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背景
- GGH (gamma-glutamyl hydrolase), also known as GH or Gamma-Glu-X carboxypeptidase, is a 318 amino acid protein that is secreted into the extracellular space and is also localized to both the lysosome and the melanosome. Functioning as a hydrolase, GGH contains one gamma-glutamyl hydrolase domain through which it catalyzes the hydrolysis of polyglutamate sidechains from pteroylpolyglutamates, specifically hydrolyzing gamma-glutamyl bonds. Via its catalytic activity, GGH may play a role in the bioavailability and metabolic activity of pteroylpolyglutamates. Polymorphisms in the gene encoding GGH are associated with rheumatoid arthritis, inflammatory bowel disease and various cancers.Synonyms: Conjugase, GH, Gamma-Glu-X carboxypeptidase
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分子量
- approx. 36 kDa
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基因ID
- 8836
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NCBI登录号
- NP_003869
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UniProt
- Q92820
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途径
- SARS-CoV-2 Protein Interactome
抗原
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