FOLR1 抗体
Quick Overview for FOLR1 抗体 (ABIN499072)
抗原
See all FOLR1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of FR-α (Y80) protein. (region surrounding Tyr80)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Folate Receptor 1 (Adult) (FOLR1) (AA 41-227) antibody
FOLR1 适用: 人 ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2G5C12 unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) (AA 25-234) antibodyFOLR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) (AA 25-93) antibodyFOLR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) antibodyFOLR1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) (Middle Region) antibodyFOLR1 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) (AA 41-227) antibodyFOLR1 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G12B7 unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) (AA 33-68), (N-Term) antibodyFOLR1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28535 unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) (AA 25-234) antibodyFOLR1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) (AA 179-228) antibodyFOLR1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Folate Receptor 1 (Adult) (FOLR1) (AA 1-257) antibodyFOLR1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
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别名
- Folate Receptor alpha
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背景
- Folate is an essential vitamin that must be obtained from food intake through intestinal absorption in mammals. Folate and reduced folic acid derivatives bind to the folate receptor (FR) family, which mediates the endocytosis of 5-methyltetrahydrofolate into the cell. The folate receptors consist of five members, α, β, γ, γ' (which is produced by alternative splicing) and δ. β-FR is attached to the membrane by a GPI anchor and is expressed in malignant tissues of epithelial and nonepithelial origin. γ-FR is expressed in tissues of hematopoietic origin, such as spleen, thymus and bone marrow. The expression pattern of δ-FR is elusive, which suggests that it is highly restricted both spatially and temporally. The α isoform of the folate receptor is used as a highly selective tumor marker and may be targeted for the delivery of therapeutic compounds to tumor cells by coupling to derivatives of folic acid.Synonyms: Adult folate-binding protein, FOLR, FOLR1, FR-alpha, Folate receptor 1, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18
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分子量
- approx. 34 kDa
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基因ID
- 2348
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NCBI登录号
- NP_000793
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UniProt
- P15328
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途径
- Dicarboxylic Acid Transport
抗原
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