FBLN3 抗体
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北京 101111
Quick Overview for FBLN3 抗体 (ABIN499069)
抗原
See all FBLN3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Fibulin-3 protein. (region surrounding Pro150)
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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应用备注
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Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- FBLN3 (Fibulin 3 (FBLN3))
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别名
- Fibulin-3
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背景
- Fibulin-3, also known as EFEMP1, is a secreted protein. Defects in the gene for Fibulin-3 cause the autosomal dominant disease Doyne honeycomb retinal dystrophy (DHRD, also known as malattia leventinese) which is characterized by yellow-white deposits (drusen) that accumulate under the retinal pigment epithelium. Fibulin-3 is not present at the site of drusen formation in normal eyes. Fibulin-5 is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion.Synonyms: DHRD, DRAD, EFEMP1, EGF-containing fibulin-like extracellular matrix protein 1, Extracellular protein S1-5, FBLN3, FBNL, Fibrillin-like protein, Fibulin 3, MLVT, MTLV, S1-5
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分子量
- approx. 55 kDa
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基因ID
- 2202
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NCBI登录号
- NP_001034437
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UniProt
- Q12805
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途径
- EGFR Signaling Pathway
抗原
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