CD3EAP 抗体
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北京 101111
Quick Overview for CD3EAP 抗体 (ABIN499063)
抗原
See all CD3EAP 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CD3EAP protein. (region surrounding Glu474)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 2-110) antibody
CD3EAP 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6A6 unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 404-454) antibodyCD3EAP 适用: 人 IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 289-404) antibodyCD3EAP 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 54-81), (N-Term) antibodyCD3EAP 适用: 人 WB 宿主: 兔 Polyclonal RB41983 unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 2-110) antibodyCD3EAP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (C-Term) antibodyCD3EAP 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (Center) antibodyCD3EAP 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (C-Term) antibodyCD3EAP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 404-454) antibodyCD3EAP 适用: 人 WB, IP, IF/ICC, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-CD3e Molecule, epsilon Associated Protein (CD3EAP) (AA 225-275) antibodyCD3EAP 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CD3EAP (CD3e Molecule, epsilon Associated Protein (CD3EAP))
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别名
- CD3EAP
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背景
- CD3EAP, also known as ASE1, CAST or PAF49, is a 510 amino acid protein that localizes to the nucleus and belongs to the eukaryotic RPA34 RNA polymerase subunit family. Existing as two alternatively spliced isoforms, CD3EAP functions as a component of the Pol I complex, specifically exhibiting DNA-dependent RNA polymerase activity and effectively catalyzing the the conversion of a nucleoside triphosphate into a diphosphate, thereby transcribing DNA into RNA. Isoform 2 of CD3EAP may be a component of the T cell receptor (TCR) complex and is subject to tyrosine phosphorylation in response to TCR stimulation. Both isoforms of CD3EAP are subject to DNA damage-dependent phosphorylation, probably by ATM or ATR.Synonyms: A34.5, ASE1, Anti-sense to ERCC-1 protein, CAST, CD3-epsilon-associated protein, DNA-directed RNA polymerase I subunit RPA34, PAF49, RNA polymerase I-associated factor PAF49
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分子量
- approx. 55 kDa
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基因ID
- 10849
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NCBI登录号
- NP_036231
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UniProt
- O15446
抗原
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