CEP290 抗体
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Quick Overview for CEP290 抗体 (ABIN499044)
抗原
See all CEP290 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CEP290 protein. (region surrounding Phe812)
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibody
Verified CEP290 适用: 人 ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyVerified CEP290 适用: 人 ELISA, IHC, ICC 宿主: 山羊 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (AA 86-156) antibodyCEP290 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyCEP290 适用: 人, 小鼠 ELISA, WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (AA 2429-2479) antibodyCEP290 适用: 人 IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (AA 950-1050) antibodyCEP290 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyCEP290 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (Internal Region) antibodyCEP290 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Centrosomal Protein 290kDa (CEP290) (AA 2429-2479) antibodyCEP290 适用: 人 WB, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CEP290 (Centrosomal Protein 290kDa (CEP290))
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别名
- CEP290
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背景
- CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells, may play a role in ciliary transport processes. CEP290 is ubiquitously expressed, strongly in placenta and weakly in brain. There are two named isoforms. Defects in CEP290 are a cause of Joubert syndrome type 5 (JBTS5) [MIM:610188], Senior-Loken syndrome type 6 (SLSN6) [MIM:610189], Leber congenital amaurosis type 10 (LCA10) [MIM:611755] and Meckel syndrome type 4 (MKS4) [MIM:611134]. Antibodies against CEP290 are present in sera from patients with cutaneous T cell lymphomas, but not in the healthy control population.Synonyms: CT87, Cancer/testis antigen 87, Centrosomal protein of 290 kDa, KIAA0373, NPHP6, Nephrocystin-6, Tumor antigen se2-2, se2-2
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分子量
- approx. 290 kDa
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基因ID
- 80184
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NCBI登录号
- NP_079390
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UniProt
- O15078
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途径
- cAMP Metabolic Process, M Phase
抗原
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