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L1CAM 抗体

This 兔 多克隆 antibody specifically detects L1CAM in WB, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN498991
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for L1CAM 抗体 (ABIN498991)

抗原

See all L1CAM 抗体
L1CAM (L1 Cell Adhesion Molecule (L1CAM))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This L1CAM antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of NCAM-L1 protein. AP21093PU-N binds to the cytoplasmic region of NCAM-L1.

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate Buffered Saline (PBS), pH ~7.2, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    L1CAM (L1 Cell Adhesion Molecule (L1CAM))

    别名

    CD171 / L1CAM

    背景

    The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.Synonyms: CAML1, MIC5, N-CAM L1, Neural cell adhesion molecule L1

    分子量

    approx. 140 kDa

    基因ID

    3897

    NCBI登录号

    NP_000416

    UniProt

    P32004

    途径

    Synaptic Membrane
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