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NPM1 抗体

NPM1 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498955
发货至: 中国
  • 抗原 See all NPM1 抗体
    NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
    适用
    • 132
    • 94
    • 66
    • 13
    • 11
    • 10
    • 9
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 125
    • 29
    • 1
    • 1
    克隆类型
    • 124
    • 33
    多克隆
    标记
    • 100
    • 10
    • 5
    • 3
    • 3
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
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    This NPM1 antibody is un-conjugated
    应用范围
    • 123
    • 62
    • 50
    • 40
    • 28
    • 27
    • 27
    • 15
    • 12
    • 11
    • 7
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of NPM protein. (region surrounding Lys230)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product NPM1 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
    别名
    Nucleophosmin (NPM1 产品)
    背景
    This gene encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.Synonyms: NPM, NPM1, Nucleolar Phosphoprotein B23, Nucleolar Protein NO38, Numatrin
    分子量
    approx. 33 kDa
    基因ID
    4869
    NCBI登录号
    NP_002511
    UniProt
    P06748
    途径
    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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