GATA1 抗体
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北京 101111
Quick Overview for GATA1 抗体 (ABIN498932)
抗原
See all GATA1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GATA-1 protein. (region surrounding Thr148)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (pSer142) antibody
GATA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (Internal Region) antibodyVerified GATA1 适用: 人, 小鼠 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (AA 123-199) antibodyGATA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) antibodyGATA1 适用: 人 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 4F5 unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (AA 39-153) antibodyGATA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (AA 1-413) antibodyGATA1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (AA 20-265) antibodyGATA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (pSer310) antibodyGATA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) (pSer310) antibodyGATA1 适用: 人, 小鼠, 大鼠, 猴, 犬, Cow, 兔, 马 WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1) antibodyGATA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G1 unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))
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别名
- GATA1
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背景
- Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroid-specific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4, expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart.Synonyms: ERYF1, Eryf1, Erythroid transcription factor, GATA-1, GATA-binding factor 1, GF-1, GF1, NF-E1 DNA-binding protein
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分子量
- approx. 43 kDa
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基因ID
- 2623
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NCBI登录号
- NP_002040
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UniProt
- P15976
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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