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GATA1 抗体 (pSer142)

The 兔 多克隆 anti-GATA1 antibody (ABIN498843) specifically detects GATA1 in IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN498843
发货至: 中国
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Quick Overview for GATA1 抗体 (pSer142) (ABIN498843)

抗原

See all GATA1 抗体
GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

适用

  • 125
  • 65
  • 42
  • 10
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 137
  • 7
  • 2

克隆类型

  • 120
  • 26
多克隆

标记

  • 69
  • 8
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
This GATA1 antibody is un-conjugated

应用范围

  • 119
  • 43
  • 40
  • 39
  • 37
  • 29
  • 28
  • 21
  • 20
  • 14
  • 10
  • 9
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 30
    • 27
    • 16
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer142

    特异性

    This antibody detects endogenous levels of p-GATA-1 protein only when phosphorylated at Ser142.

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GATA1 (GATA Binding Protein 1 (Globin Transcription Factor 1) (GATA1))

    别名

    GATA1

    背景

    Members of the GATA family share a conserved zinc finger DNA-binding domain and are capable of binding the WGATAR consensus sequence. GATA-1 is erythroidspecific and is responsible for the regulated transcription of erythroid genes. It is an essential component in the generation of the erythroid lineage. GATA-2 is expressed in embryonic brain and liver, HeLa and endothelial cells, as well as erythroid cells. Studies with a modified GATA consensus sequence, AGATCTTA, have shown that GATA-2 and GATA-3 recognize this mutated consensus while GATA-1 has poor recognition of this sequence. This indicates broader regulatory capabilities of GATA-2 and GATA-3 than GATA-1. GATA-3 is highly expressed in T lymphocytes. GATA-4, GATA-5 and GATA-6 comprise a subfamily of transcription factors. GATA-4 and GATA-6 are found in heart, pancreas and ovary, lung and liver tissues exhibit GATA-6, but not GATA-4, expression. GATA-5 expression has been observed in differentiated heart and gut tissues and is present throughout the course of development in the heart.Synonyms: ERYF1, Eryf1, Erythroid transcription factor, GATA-1, GATA-binding factor 1, GF-1, GF1, NF-E1 DNA-binding protein

    分子量

    approx. 43 kDa

    基因ID

    2623

    NCBI登录号

    NP_002040

    UniProt

    P15976

    途径

    Cellular Response to Molecule of Bacterial Origin
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