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CDK1 抗体 (pTyr15)

Name: CDK1 抗体 (pTyr15)
SKU: ABIN498742
Availability: OutOfStock

CDK1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated

Western blot (WB) analyzes of p-Cdk1/Cdc2 antibody in extracts from HepG2 cells. (CDK1 抗体 (pTyr15))

1 image

产品编号 ABIN498742

发货至: 中国

Datasheet as PDF

抗原 See all CDK1 抗体

CDK1 (Cyclin-Dependent Kinase 1 (CDK1))
抗原表位
34

29

25

24

18

16

13

9

8

8

8

7

6

6

5

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pTyr15
适用
310

175

109

36

34

31

25

20

15

12

11

11

11

9

7

6

4

3

1

1

1

1

1

1

1

1

1

1

1
人, 小鼠, 大鼠
宿主
261

59
兔
Compatible Secondaries
克隆类型
251

69
多克隆
标记
155

27

17

15

11

10

8

8

8

8

8

8

4

4

4

4

4

3

2

2

2

2

2

2

2
This CDK1 antibody is un-conjugated
应用范围
255

122

66

56

54

53

51

43

40

20

18

16

6

6

4

4

3

2

2

2

2

1

1

1
Western Blotting (WB)

特异性

This antibody detects endogenous levels of CDC2 protein only when phosphorylated at Tyr15.

交叉反应（详细）

Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

纯化方法

Affinity chromatography

纯度

> 95 % by SDS-PAGE

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anti-Cyclin-Dependent Kinase 1 (CDK1) (pTyr15) antibody
CDK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 1-297) antibody
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CDK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G10 unconjugated

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CDK1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 211-297) antibody
CDK1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 8F1 unconjugated

anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 1-297) antibody
CDK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin-Dependent Kinase 1 (CDK1) antibody
CDK1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 2G9 unconjugated

anti-Cyclin-Dependent Kinase 1 (CDK1) (AA 66-297) antibody
CDK1 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1,0 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

CDK1 (Cyclin-Dependent Kinase 1 (CDK1))

别名

CDK1 (CDK1 产品)

别名

CDC2 antibody, CDC28A antibody, P34CDC2 antibody, Cdc2 antibody, Cdc2a antibody, p34 antibody, cdc2 antibody, wu:fc30e01 antibody, zgc:92032 antibody, PSTAIR antibody, cdc-2 antibody, cdc2-a antibody, cdc28a antibody, cdc2x1.1 antibody, p34cdc2 antibody, xcdc2 antibody, 5363 antibody, CDCDm antibody, CDK1 antibody, CDK1/CDC2 antibody, CG5363 antibody, Cdk-1 antibody, Cdk1 antibody, Dcdc2 antibody, Dm cdc2 antibody, DmCdc2 antibody, DmCdk1 antibody, Dmcdc2 antibody, Dmel\\CG5363 antibody, cdc antibody, cdc2Dm antibody, cdk1 antibody, dCdk1 antibody, group 4 antibody, l(2)31Eh antibody, CDC2A antibody, CDC2AAT antibody, CDK2 antibody, CDKA1 antibody, CDKA;1 antibody, CYCLIN-DEPENDENT KINASE A;1 antibody, cell division control 2 antibody, cdc2-b antibody, cdc2a antibody, cdc2x1.2 antibody, POL3 antibody, pold antibody, cyclin dependent kinase 1 antibody, cyclin dependent kinase like 1 antibody, Cell division control protein 2 1 antibody, cyclin-dependent kinase 1 antibody, cyclin-dependent kinase 1 S homeolog antibody, Cyclin-dependent kinase 1 antibody, cell division control 2 antibody, cell division control protein2 homolog antibody, cyclin-dependent kinase 1 L homeolog antibody, polymerase (DNA directed), delta 1, catalytic subunit L homeolog antibody, cyclin-dependent protein kinase Cdk1/Cdc2 antibody, CDK1 antibody, CDKL1 antibody, POPTR_0004s14080g antibody, Cdk1 antibody, cdk1 antibody, cdk1.S antibody, CDC2 antibody, cdc2 antibody, cdk-1 antibody, cdk1.L antibody, pold1.L antibody

背景

Cdc2, an evolutionarily conserved serine/threonine-specific protein kinase, is essential in the cell cycle transition from G2 to M phase. Cdc2 is regulated by association with B-type cyclins and by reversible phosophorylation. Cyclin B binding facilitates the phosphorylation of Cdc2 p34 on three regulatory sites: threonine 14, tyrosine 15, and threonine 161. In higher eukaryotes, Cdc2 is negatively regulated by phosphorylation of two residues located in the ATP-binding site, Thr 14 and Tyr 15. Cdc2 is positively regulated by the cyclin-dependent phosphorylation of Thr 161. Both phosphorylation and de- phosphorylation at Thr 161 are required for progression through the cell cycle.Synonyms: CDC2, CDC28A, CDK1, CDKN1, Cell division control protein 2 homolog, Cell division protein kinase 1, Cyclin-dependent kinase 1, P34CDC2, p34 protein kinase

分子量

approx. 34 kDa

基因ID

983

NCBI登录号

NP_001777

UniProt

P06493

途径

Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Toll-Like Receptors Cascades, Synthesis of DNA