NCOA1 抗体 (pTyr529)
Our Local Distributor
北京 101111
Quick Overview for NCOA1 抗体 (pTyr529) (ABIN498717)
抗原
See all NCOA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pTyr529
-
特异性
- This antibody detects endogenous levels of c-Src protein only when phosphorylated at Tyr529.
-
交叉反应 (详细)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
-
纯度
- > 95 % by SDS-PAGE
-
-
-
-
应用备注
-
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1,0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
-
别名
- SRC1
-
背景
- The major translational products of the members of the Src gene family identified to date are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences, thereby distinguishing this group from the receptor class of tyrosine kinases. Members of this group include c-Src, c-Yes, Fyn, Lck, Lyn, Blk and c-Fgr. The major Src gene encoded protein, pp60Src, is expressed in a broad range of tissue and cell types, although the highest levels of pp60Src are detected in neuronal tissues and platelets. pp60Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.Synonyms: Proto-oncogene c-Src, Proto-oncogene tyrosine-protein kinase Src, c-Src, pp60c-src
-
分子量
- approx. 60 kDa
-
基因ID
- 6714
-
NCBI登录号
- NP_005408
-
UniProt
- P12931
-
途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
-