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NCOA1 抗体 (pTyr529)

This anti-NCOA1 antibody is a 兔 多克隆 antibody detecting NCOA1 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN498717
发货至: 中国

Quick Overview for NCOA1 抗体 (pTyr529) (ABIN498717)

抗原

See all NCOA1 抗体
NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This NCOA1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pTyr529

    特异性

    This antibody detects endogenous levels of c-Src protein only when phosphorylated at Tyr529.

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))

    别名

    SRC1

    背景

    The major translational products of the members of the Src gene family identified to date are membrane-associated tyrosine protein kinases that lack transmembrane and external amino acid sequences, thereby distinguishing this group from the receptor class of tyrosine kinases. Members of this group include c-Src, c-Yes, Fyn, Lck, Lyn, Blk and c-Fgr. The major Src gene encoded protein, pp60Src, is expressed in a broad range of tissue and cell types, although the highest levels of pp60Src are detected in neuronal tissues and platelets. pp60Src may play a role in events associated with both neuronal differentiation and maintenance of mature neuronal cell functions.Synonyms: Proto-oncogene c-Src, Proto-oncogene tyrosine-protein kinase Src, c-Src, pp60c-src

    分子量

    approx. 60 kDa

    基因ID

    6714

    NCBI登录号

    NP_005408

    UniProt

    P12931

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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