Cofilin 抗体 (pSer3)
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Quick Overview for Cofilin 抗体 (pSer3) (ABIN498706)
抗原
See all Cofilin (CFL1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer3
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特异性
- This antibody detects endogenous levels of Cofilin protein only when phosphorylated at Ser3.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Cofilin 1 (CFL1) antibody
KO Validated CFL1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 1-166) antibodyCFL1 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Cofilin 1 (CFL1) (AA 3-161) antibodyCFL1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 70-98) antibodyCFL1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB23947 unconjugated
anti-Cofilin 1 (CFL1) (AA 1-100) antibodyCFL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (C-Term) antibodyCFL1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 4-32), (N-Term) antibodyCFL1 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20525 unconjugated
anti-Cofilin 1 (CFL1) (AA 4-32) antibodyCFL1 适用: 人, 小鼠 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 1 (CFL1) (AA 1-166) antibodyCFL1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal AT1C1 unconjugated
anti-Cofilin 1 (CFL1) (AA 4-144) antibodyCFL1 适用: 人 IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Cofilin (CFL1) (Cofilin 1 (CFL1))
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别名
- Cofilin-1
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背景
- Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly, essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous F-Actin by bridging two longitudinally-associated Actin subunits, changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser 3 by factors like opsonized zymosan. LIM kinase 1 (LIMK-1), a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerize F-Actin.Synonyms: 18 kDa phosphoprotein, CFL, CFL1, Cofilin non-muscle isoform, p18
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分子量
- approx. 19 kDa
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基因ID
- 1072
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NCBI登录号
- NP_005498
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UniProt
- P23528
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途径
- Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
抗原
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