×
我们推荐在您的浏览器上开启Javascript,以获得最佳效果。
Cofilin 抗体 (pSer3)
CFL1
适用: 人, 小鼠, 大鼠
WB, IHC (p)
宿主: 兔
Polyclonal
unconjugated
Cofilin抗体详情
(hide)
抗原
See all Cofilin (CFL1) 抗体
Cofilin (CFL1)
(Cofilin 1 (CFL1))
抗原表位
All epitopes for Cofilin 抗体
pSer3
适用
All reactivities for Cofilin 抗体
人, 小鼠, 大鼠
宿主
All hosts for Cofilin 抗体
兔
克隆类型
All clonalities for Cofilin 抗体
多克隆
标记
All conjugates for Cofilin 抗体
This Cofilin antibody is un-conjugated
应用范围
All applications for Cofilin 抗体
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
特异性
This antibody detects endogenous levels of Cofilin protein only when phosphorylated at Ser3.
交叉反应 (详细)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
纯化方法
Affinity chromatography
纯度
> 95 % by SDS-PAGE
Top Product
Discover our top product CFL1 Primary Antibody
Alternatives
(show)
使用细节
(hide)
应用备注
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
(hide)
浓度
1,0 mg/mL
缓冲液
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Cofilin目标详情
(hide)
抗原
Cofilin (CFL1)
(Cofilin 1 (CFL1))
别名
Cofilin-1 (CFL1 产品 )
别名
cfl1 antibody, xac1 antibody, xac2 antibody, cfl antibody, cb86 antibody, sb:cb86 antibody, zgc:56501 antibody, wu:fb18a04 antibody, wu:fk77b03 antibody, 12/8 antibody, ADF antibody, ADF/cofilin antibody, Adf antibody, CG4254 antibody, Cadf antibody, D-cof antibody, D61 antibody, Dmel\\CG4254 antibody, T8 antibody, Tsr antibody, cofilin antibody, cofilin/ADF antibody, cofilin/actin depolymerizing factor homolog antibody, l(2)03101 antibody, l(2)k03101 antibody, l(2)k05633 antibody, l(2)k13409 antibody, ntf antibody, CFL antibody, AA959946 antibody, Cof antibody, CFL1 antibody, cofilin 1 (non-muscle) L homeolog antibody, cofilin 1 (non-muscle) antibody, cofilin 1 (non-muscle), like antibody, cofilin 1 antibody, twinstar antibody, cofilin antibody, cofilin 1, non-muscle antibody, Contrafreeloading antibody, cfl1.L antibody, cfl1 antibody, cfl1l antibody, CFL1 antibody, tsr antibody, COF1 antibody, TSTA_042790 antibody, Cfl1 antibody, CFL antibody
背景
Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly, essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous F-Actin by bridging two longitudinally-associated Actin subunits, changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser 3 by factors like opsonized zymosan. LIM kinase 1 (LIMK-1), a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerize F-Actin.Synonyms: 18 kDa phosphoprotein, CFL, CFL1, Cofilin non-muscle isoform, p18
分子量
approx. 19 kDa
基因ID
1072
NCBI登录号
NP_005498
UniProt
P23528
途径
Regulation of Cell Size , Tube Formation , Protein targeting to Nucleus , CXCR4-mediated Signaling Events
Recently viewed
(hide)