ATP7A 抗体
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Quick Overview for ATP7A 抗体 (ABIN498686)
抗原
See all ATP7A 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of ATP7A protein. (region surrounding His640)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (Atto 390)
ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 Atto 390
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (Atto 488)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 Atto 488
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (APC)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 APC
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (Biotin)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 Biotin
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (Atto 594)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 Atto 594
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (PerCP)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 PerCP
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (FITC)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 FITC
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (PE)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 PE
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 42-61) antibody (HRP)ATP7A 适用: 人 WB, IHC, IP, IF, ICC 宿主: 小鼠 Monoclonal S60-4 HRP
anti-ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A) (AA 242-285) antibodyATP7A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
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别名
- ATP7A
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背景
- The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7A functions as a transmembrane copper-translocating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney. Polarized epithelial cells such as Madin-Darby canine kidney cells are a physiologically relevant model for systemic copper absorption and reabsorption in vivo. Although ATP7A is not detectable in most normal tissues it is expressed in a considerable fraction of many common tumor types. Increased expression of ATP7A renders cells resistant to cisplatin and carboplatin.Synonyms: Copper pump 1, Copper-transporting ATPase 1, MC1, MNK, Menkes disease-associated protein
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基因ID
- 538
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NCBI登录号
- NP_000043
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UniProt
- Q04656
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途径
- Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
抗原
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