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ATP7A 抗体

ATP7A 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498686
发货至: 中国
  • 抗原 See all ATP7A 抗体
    ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
    适用
    • 50
    • 29
    • 28
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 36
    • 14
    • 1
    • 1
    克隆类型
    • 38
    • 14
    多克隆
    标记
    • 25
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ATP7A antibody is un-conjugated
    应用范围
    • 42
    • 19
    • 14
    • 13
    • 13
    • 13
    • 13
    • 11
    • 7
    • 4
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of ATP7A protein. (region surrounding His640)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product ATP7A Primary Antibody
  • 应用备注
    Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ATP7A (ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
    别名
    ATP7A (ATP7A 产品)
    别名
    ATP7A antibody, cal antibody, wu:fc43e01 antibody, zgc:153422 antibody, zgc:158633 antibody, DDBDRAFT_0218568 antibody, DDBDRAFT_0235190 antibody, DDB_0218568 antibody, DDB_0235190 antibody, atpase antibody, Atp7a antibody, kal antibody, atp7a antibody, DSMAX antibody, MK antibody, MNK antibody, SMAX3 antibody, Blo antibody, DXHXS1608e antibody, I14 antibody, Mo antibody, blotchy antibody, br antibody, brindled antibody, mottled antibody, Mnk antibody, ATPase copper transporting alpha antibody, ATPase, Cu++ transporting, alpha polypeptide antibody, P-type ATPase antibody, ATP synthase subunit a antibody, copper-transporting ATPase 1 antibody, ATP7A antibody, atp7a antibody, LOC100049514 antibody, Atp7a antibody, LOC412379 antibody
    背景
    The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7A functions as a transmembrane copper-translocating P-type ATPase and plays a vital role in systemic copper absorption in the gut and copper reabsorption in the kidney. Polarized epithelial cells such as Madin-Darby canine kidney cells are a physiologically relevant model for systemic copper absorption and reabsorption in vivo. Although ATP7A is not detectable in most normal tissues it is expressed in a considerable fraction of many common tumor types. Increased expression of ATP7A renders cells resistant to cisplatin and carboplatin.Synonyms: Copper pump 1, Copper-transporting ATPase 1, MC1, MNK, Menkes disease-associated protein
    基因ID
    538
    NCBI登录号
    NP_000043
    UniProt
    Q04656
    途径
    Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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