Acetylcholinesterase 抗体
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Quick Overview for Acetylcholinesterase 抗体 (ABIN498685)
抗原
See all Acetylcholinesterase (AChE) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of AChE I protein. (region surrounding Lys585)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Acetylcholinesterase (AChE) (C-Term) antibody
Verified AChE 适用: 人 WB, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 398-617) antibodyAChE 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (C-Term) antibodyAChE 适用: 人, 小鼠, 大鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 157-332) antibodyAChE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 147-175), (N-Term) antibodyAChE 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB16792 unconjugated
anti-Acetylcholinesterase (AChE) (AA 521-614) antibodyAChE 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) antibodyAChE 适用: 人 IHC, ELISA, IHC (p) 宿主: 绵羊 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 53-162) antibodyAChE 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Acetylcholinesterase (AChE) (AA 587-611), (C-Term) antibodyAChE 适用: 人, 小鼠, 大鼠, Green Monkey WB 宿主: 小鼠 Monoclonal 684CT8-3-4 unconjugated
anti-Acetylcholinesterase (AChE) (AA 366-554) antibodyAChE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Acetylcholinesterase (AChE)
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别名
- Acetylcholinesterase
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背景
- Acetylcholinesterase (AChE) hydrolyzes acetylcholine at synaptic junctions. Alternative mRNA splicing gives rise to three forms of AChE. The T form, also known as the asymmetric form, is soluble and is present in synapses. The H form is also known as the globular form and is present on the outer surfaces of cell membranes. The R form is not known to be a functional species. AChE globular form subunits are GPI-anchored to cell membranes and asymmetric subunits are anchored to basal lamina components by a collagen tail. The catalytic subunits of AChE are oligomers composed of disulfide-linked homodimers. The loss of AChE from cholinergic and noncholinergic neurons in the brain is seen in patients with Alzheimer's disease. However, AChE activity is increased around amyloid plaques, which may be due to a disturbance in calcium homeostasis involving the opening of L-type voltage-dependent calcium channels.Synonyms: AChE, Acetylcholine Esterase, Acetylcholine-Esterase
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分子量
- approx. 70 kDa
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基因ID
- 43
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NCBI登录号
- NP_000656
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UniProt
- P22303
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途径
- Skeletal Muscle Fiber Development
抗原
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