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BMP3 抗体

The 兔 多克隆 anti-BMP3 antibody is suitable to detect BMP3 in samples from 人, 大鼠 和 小鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN498674
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BMP3 抗体 (ABIN498674)

抗原

See all BMP3 抗体
BMP3 (Bone Morphogenetic Protein 3 (BMP3))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

  • 58
  • 9
多克隆

标记

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This BMP3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of BMP-3 protein. (region surrounding Glu306)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity-Chromatography using epitope-specific immunogen
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BMP3 (Bone Morphogenetic Protein 3 (BMP3))

    别名

    BMP3

    背景

    Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.Synonyms: BMP-3A, BMP3A, Bone morphogenetic protein 3, Osteogenin

    分子量

    approx. 50 kDa

    基因ID

    651

    NCBI登录号

    NP_001192

    UniProt

    P12645
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