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BMP8B 抗体

The 兔 多克隆 anti-BMP8B antibody (ABIN498669) specifically detects BMP8B in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN498669
发货至: 中国
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Quick Overview for BMP8B 抗体 (ABIN498669)

抗原

See all BMP8B (BMP8) 抗体
BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))

适用

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  • 9
  • 5
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宿主

  • 40
  • 6

克隆类型

  • 40
  • 6
多克隆

标记

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  • 2
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  • 1
  • 1
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  • 1
  • 1
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  • 1
  • 1
  • 1
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This BMP8B antibody is un-conjugated

应用范围

  • 36
  • 18
  • 14
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  • 7
  • 6
  • 6
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  • 4
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of BMP-8 protein. (region surrounding Glu90)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BMP8B (BMP8) (Bone Morphogenetic Protein 8B (BMP8))

    别名

    BMP8B

    背景

    Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 is thought to be involved in early development, as detectable expression has not been found in adult organs. Two BMP-8 proteins exist, namely BMP-8A and BMP-8B (also designated OP-2), and are encoded by two distinct genes.Synonyms: BMP-8B, Bone morphogenetic protein 8B, OP2, Osteogenic protein 2

    基因ID

    656

    NCBI登录号

    NP_001711

    UniProt

    P34820
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