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Cardiotrophin 1 抗体

CTF1 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498664
发货至: 中国
  • 抗原 See all Cardiotrophin 1 (CTF1) 抗体
    Cardiotrophin 1 (CTF1)
    适用
    • 73
    • 23
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 75
    • 6
    • 1
    克隆类型
    • 76
    • 6
    多克隆
    标记
    • 35
    • 13
    • 9
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    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    This Cardiotrophin 1 antibody is un-conjugated
    应用范围
    • 54
    • 31
    • 28
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
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    • 1
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    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Cardiotrophin-1 protein. (region surrounding His31)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product CTF1 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Cardiotrophin 1 (CTF1)
    别名
    Cardiotrophin-1 (CTF1 产品)
    别名
    CTF1 antibody, ct1 antibody, ct-1 antibody, ctf2 antibody, CT-1 antibody, CT1 antibody, cardiotrophin 1 antibody, cardiotrophin-1 antibody, CTF1 antibody, ctf1 antibody, Ctf1 antibody, LOC100736818 antibody
    背景
    Cardiotrophin-1 (CT-1) is a member of the IL-6 family of cytokines, which signal through gp130 receptor complexes. gp130 complexes with several different receptor subunits to transmit signals from Cardiotrophin-1, IL-6, LIF, OSM, CNTF and IL-11. Cardiotrophin-1 binds to and activates the leukemia inhibitory factor (LIF) receptor/gp130 receptor complex and has been shown to induce hypertrophy in cardiac myocytes in vitro. Cardiotrophin-1, a secreted protein expressed at high levels in myocardium during cardiogenesis, has been shown to promote proliferation and survival of embryonic cardiomyocytes, suggesting a role for Cardiotrophin-1 in the activation of gp130 during cardiac development. Cardiotrophin-1 is highly expressed in heart, prostate, ovary and skeletal muscle. Lower levels of expression are seen in lung, kidney, pancreas, thymus, testis and small intestine.Synonyms: CT-1, CTF1
    分子量
    approx. 21 kDa
    基因ID
    1489
    NCBI登录号
    NP_001136016
    UniProt
    Q16619
    途径
    JAK/STAT Signaling
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