GAP43 抗体
Quick Overview for GAP43 抗体 (ABIN498648)
抗原
See all GAP43 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of GAP43 protein. (region surrounding Ala35)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Growth Associated Protein 43 (GAP43) (AA 9-100) antibody
GAP43 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-274) antibodyGAP43 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C11 unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 1-238) antibodyGAP43 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (pSer41) antibodyGAP43 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) (AA 8-226) antibodyGAP43 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Associated Protein 43 (GAP43) antibodyGAP43 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal Mix unconjugated
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应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GAP43 (Growth Associated Protein 43 (GAP43))
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别名
- GAP43
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背景
- GAP-43 (growth associated protein 43, B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1) is a crucial component for regenerative response in the nervous system that is present at high levels in neuronal growth cones during development and axonal regeneration. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron-specific ELAV/Hu family member, HuD, interacts with and stabilizes GAP-43 mRNA in developing neurons and leads to increased levels of GAP-43 protein. Heterozygous GAP-43 knockout mice with GAP-43 levels reduced by one-half display significant memory impairments in cued conditioning or on tests of nociceptive or auditory perception.Synonyms: Axonal membrane protein GAP-43, Growth-associated protein 43, Neural phosphoprotein B-50, Neuromodulin, PP46
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分子量
- approx. 38, 43 kDa
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基因ID
- 2596
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NCBI登录号
- NP_002036
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UniProt
- P17677
抗原
-
