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IL-11 抗体

This anti-IL-11 antibody is a 兔 多克隆 antibody detecting IL-11 in IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN498569
发货至: 中国

Quick Overview for IL-11 抗体 (ABIN498569)

抗原

See all IL-11 (IL11) 抗体
IL-11 (IL11) (Interleukin 11 (IL11))

适用

人, 小鼠, 大鼠

宿主

  • 46
  • 23
  • 1
  • 1

克隆类型

  • 47
  • 24
多克隆

标记

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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL-11 antibody is un-conjugated

应用范围

  • 56
  • 36
  • 19
  • 17
  • 14
  • 13
  • 13
  • 12
  • 4
  • 4
  • 4
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  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of IL-11 protein. (region surrounding Gly27)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity-chromatography using epitope-specific immunogen.
  • 应用备注

    Immunohistochemistry on Paraffin Sections: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    IL-11 (IL11) (Interleukin 11 (IL11))

    别名

    Interleukin-11 / IL11

    背景

    Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.Synonyms: AGIF, Adipogenesis inhibitory factor, IL-11

    基因ID

    3589

    NCBI登录号

    NP_000632

    UniProt

    P20809

    途径

    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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