SLC22A6 抗体
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北京 101111
Quick Overview for SLC22A6 抗体 (ABIN498567)
抗原
See all SLC22A6 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of OAT1 protein. (region surrounding Leu304)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Solute Carrier Family 22 Member 6 (SLC22A6) (AA 534-550), (C-Term) antibody
SLC22A6 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (AA 513-541), (C-Term) antibodySLC22A6 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23819 unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (AA 451-550) antibodySLC22A6 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F2 unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (C-Term) antibodySLC22A6 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (C-Term) antibodySLC22A6 适用: 人, 大鼠, 小鼠, Cow, 豚鼠, 马, 兔, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) antibodySLC22A6 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (Internal Region) antibodySLC22A6 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (AA 534-550) antibodySLC22A6 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (N-Term) antibodySLC22A6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 22 Member 6 (SLC22A6) (AA 513-541) antibodySLC22A6 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SLC22A6 (Solute Carrier Family 22 Member 6 (SLC22A6))
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别名
- SLC22A6 / OAT1
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背景
- SOAT1 (sterol O-acyltransferase 1), also designated ACAT1, is a homotetrameric enzyme that catalyzes the formation of cholesterol esters from cholesterol and long-chain fatty acyl coenzyme A. The gene encoding human SOAT1 maps to chromosome 1 and is expressed as a protein that localizes to the endoplasmic reticulum (ER) in several tissues, including liver, kidney, adrenal glands and macrophages. SOAT1 is involved in cellular cholesterol homeostasis as well as in foam cell formation and the subsequent progression of atherosclerosis. Several SOAT inhibitors have been developed for the treatment of atherosclerosis. SOAT2 (sterol Oacyltransferase 2), also known as ACAT2 (acyl coenzyme A), participates in lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. SOAT2 is an integral membrane protein that localizes to the ER of human intestinal cells. SOAT2 deficiency contributes to severe mental retardation and hypotonus.Synonyms: Organic anion transporter 1, PAH transporter, PAHT, ROAT, Renal organic anion transporter 1, Solute carrier family 22 member 6
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分子量
- approx. 65 kDa
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基因ID
- 9356
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NCBI登录号
- NP_004781
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UniProt
- Q4U2R8
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途径
- Dicarboxylic Acid Transport
抗原
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