NPY 抗体
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北京 101111
Quick Overview for NPY 抗体 (ABIN498562)
抗原
See all NPY 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of NPY protein. (region surrounding Pro94)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Neuropeptide Y (NPY) (AA 30-97) antibody
NPY 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y (NPY) (AA 1-97) antibodyNPY 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y (NPY) (AA 29-97) antibodyNPY 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-Neuropeptide Y (NPY) (AA 29-64) antibodyNPY 适用: 人, 大鼠, 小鼠, 小鸡 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Neuropeptide Y (NPY) (AA 29-97) antibodyNPY 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Neuropeptide Y (NPY) antibodyMicroarray verified NPY 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB615852 unconjugated
anti-Neuropeptide Y (NPY) antibodyNPY 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Neuropeptide Y (NPY) (AA 31-98) antibodyNPY 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NPY (Neuropeptide Y (NPY))
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别名
- Neuropeptide Y / NPY
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背景
- A gene located on chromosome 7p15.1 encodes a 36-amino acid protein designated NPY (Neuropeptide Y). NPY consists of a polyproline stretch followed by an amphipathic alphahelix. NPY shares a 50 % amino acid homology with pancreatic polypeptide gene (PP). The NPY hormone family consists of NPY, PP and peptide YY. NPY is expressed throughout the central and peripheral nervous system, particularly in the deep layers of the cortex and smaller cell bodies in the white matter. NPY interacts with the Y-receptor family of G-protein coupled receptors. NPY interacts with NPY receptor Y1 to increase corticotropin levels and decrease noradrenaline levels in the hypothalamus. Through interactions in the hypothalus, NPY plays important roles in the regulation of energy balance by stimulating food intake. NPY favors energy storage by increasing lipoprotein lipase activity in white adipose tissue. A leucine(7)-to- proline(7) polymorphism has been implicated in an increase in alcohol preference, and decrease in cholesterol metabolism.
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分子量
- approx. 11 kDa
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基因ID
- 4852
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NCBI登录号
- NP_000896
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UniProt
- P01303
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途径
- Feeding Behaviour
抗原
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