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NPY 抗体

NPY 适用: 人, 大鼠, 小鼠 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498562
发货至: 中国
  • 抗原 See all NPY 抗体
    NPY (Neuropeptide Y (NPY))
    适用
    • 53
    • 34
    • 33
    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 43
    • 11
    • 6
    克隆类型
    • 48
    • 12
    多克隆
    标记
    • 36
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NPY antibody is un-conjugated
    应用范围
    • 44
    • 28
    • 22
    • 13
    • 13
    • 10
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of NPY protein. (region surrounding Pro94)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product NPY Primary Antibody
  • 应用备注
    Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NPY (Neuropeptide Y (NPY))
    别名
    Neuropeptide Y / NPY (NPY 产品)
    别名
    0710005A05Rik antibody, PYY4 antibody, NPY02 antibody, RATNPY antibody, RATNPY02 antibody, si:dkey-22m8.5 antibody, npy antibody, npyb antibody, preproNPY antibody, pyy4 antibody, xnpy antibody, npya antibody, MGC86288 antibody, prepronpy antibody, NPY antibody, NPY1 antibody, neuropeptide Y antibody, neuropeptide Y S homeolog antibody, neuropeptide Y L homeolog antibody, Npy antibody, NPY antibody, npy antibody, npy.S antibody, npy.L antibody, LOC100533423 antibody
    背景
    A gene located on chromosome 7p15.1 encodes a 36-amino acid protein designated NPY (Neuropeptide Y). NPY consists of a polyproline stretch followed by an amphipathic alphahelix. NPY shares a 50 % amino acid homology with pancreatic polypeptide gene (PP). The NPY hormone family consists of NPY, PP and peptide YY. NPY is expressed throughout the central and peripheral nervous system, particularly in the deep layers of the cortex and smaller cell bodies in the white matter. NPY interacts with the Y-receptor family of G-protein coupled receptors. NPY interacts with NPY receptor Y1 to increase corticotropin levels and decrease noradrenaline levels in the hypothalamus. Through interactions in the hypothalus, NPY plays important roles in the regulation of energy balance by stimulating food intake. NPY favors energy storage by increasing lipoprotein lipase activity in white adipose tissue. A leucine(7)-to- proline(7) polymorphism has been implicated in an increase in alcohol preference, and decrease in cholesterol metabolism.
    分子量
    approx. 11 kDa
    基因ID
    4852
    NCBI登录号
    NP_000896
    UniProt
    P01303
    途径
    Feeding Behaviour
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