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Cholecystokinin 抗体

This 兔 多克隆 antibody specifically detects Cholecystokinin in IHC (p). It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN498541
发货至: 中国
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Quick Overview for Cholecystokinin 抗体 (ABIN498541)

抗原

See all Cholecystokinin (CCK) 抗体
Cholecystokinin (CCK)

适用

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人, 大鼠, 小鼠

宿主

  • 37
  • 15

克隆类型

  • 37
  • 15
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
  • 1
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This Cholecystokinin antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of CCK protein. (region surrounding Val46)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Cholecystokinin (CCK)

    别名

    Cholecystokinin / CCK

    背景

    CCK (cholecystokinin) is a 115 amino acid secreted protein belonging to the gastrin/cholecystokinin family. CCK has been shown to stimulate the growth of pancreatic cancer. As a peptide hormone, CCK induces gallbladder contraction and the release of pancreatic enzymes in the gut. Binding of CCK to CCK-A receptors stimulates amylase release from the pancreas, while binding to CCK-B receptors stimulates gastric acid secretion. The function of CCK in the brain is not clear. The CCK precursor is cleaved by proteases to produce a number of active cholecystokinins including CCK58, CCK58 desnonopeptide, CCK39, CCK33, CCK25, CCK18, CCK12, CCK8, CCK7 and CCK5.

    分子量

    approx. 13 kDa

    基因ID

    885

    NCBI登录号

    NP_000720

    UniProt

    P06307

    途径

    TCR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Feeding Behaviour
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