SGCB 抗体
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Quick Overview for SGCB 抗体 (ABIN498534)
抗原
See all SGCB 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Sarcoglycan-β protein. (region surrounding Val136)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (AA 87-196) antibody
SGCB 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (AA 165-260) antibodySGCB 适用: 小鼠, 大鼠 IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (AA 87-197) antibodySGCB 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (AA 1-318) antibodySGCB 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (N-Term) antibodySGCB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (AA 124-219) antibodySGCB 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (AA 1-319) antibodySGCB 适用: 人 WB, ELISA, IHC, IHC (fro) 宿主: 小鼠 Monoclonal 1E3 unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (AA 94-318) antibodySGCB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (AA 180-229) antibodySGCB 适用: 人, 小鼠, 大鼠, Cow, 兔, Pig, 豚鼠, 马, Hamster, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) (Internal Region) antibodySGCB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immnohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))
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别名
- SGCB (Beta-Sarcoglycan)
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背景
- The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.Synonyms: 43 kDa dystrophin-associated glycoprotein, 43DAG, A3b, Beta sarcoglycan, Beta-SG
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分子量
- approx. 38 kDa
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基因ID
- 6443
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NCBI登录号
- NP_000223
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UniProt
- Q16585
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途径
- Myometrial Relaxation and Contraction, Maintenance of Protein Location
抗原
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