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SGCB 抗体

SGCB 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498534
发货至: 中国
  • 抗原 See all SGCB 抗体
    SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))
    适用
    • 32
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    • 23
    • 5
    • 5
    • 4
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    • 3
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    • 2
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    • 1
    • 1
    人, 小鼠
    宿主
    • 38
    • 3
    克隆类型
    • 38
    • 3
    多克隆
    标记
    • 18
    • 2
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    • 2
    • 2
    • 2
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    • 2
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    • 1
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    This SGCB antibody is un-conjugated
    应用范围
    • 15
    • 13
    • 13
    • 11
    • 8
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Sarcoglycan-β protein. (region surrounding Val136)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product SGCB Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immnohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SGCB (Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB))
    别名
    SGCB (Beta-Sarcoglycan) (SGCB 产品)
    别名
    A3b antibody, LGMD2E antibody, SGC antibody, 43kDa antibody, AI747103 antibody, AI844814 antibody, beta-SG antibody, CG5657 antibody, DmSCG-beta antibody, Dmel\\CG5657 antibody, dscgbeta antibody, scg-beta antibody, beta-sarcoglycan antibody, fa03a05 antibody, wu:fa03a05 antibody, zgc:110833 antibody, sarcoglycan beta antibody, sarcoglycan, beta (dystrophin-associated glycoprotein) antibody, Sarcoglycan beta antibody, SarcoGlycaN antibody, uncharacterized LOC5567384 antibody, beta-sarcoglycan antibody, sarcoglycan, beta antibody, sarcoglycan beta L homeolog antibody, SGCB antibody, Sgcb antibody, Scgbeta antibody, sgn-1 antibody, LOC5567384 antibody, CpipJ_CPIJ006944 antibody, sgcb.L antibody, sgcb antibody
    背景
    The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac and smooth muscle fibers. Four sarcoglycan subunit proteins, designated α-, β-, γ- and δ-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, β- and δ-sarcoglycans are associated with ε-sarcoglycan, a glycoprotein homologous to α-sarcoglycan. Additionally, a complete deficiency in δ-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy.Synonyms: 43 kDa dystrophin-associated glycoprotein, 43DAG, A3b, Beta sarcoglycan, Beta-SG
    分子量
    approx. 38 kDa
    基因ID
    6443
    NCBI登录号
    NP_000223
    UniProt
    Q16585
    途径
    Myometrial Relaxation and Contraction, Maintenance of Protein Location
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