alpha Defensin 1 抗体
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- 抗原 See all alpha Defensin 1 (DEFA1) 抗体
- alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This alpha Defensin 1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- This antibody detects endogenous levels of Defensin α1 protein. (region surrounding Ser52)
- 交叉反应 (详细)
- Species reactivity (tested):Human.
- 纯化方法
- Affinity chromatography using epitope-specific immunogen
- 纯度
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product DEFA1 Primary Antibody
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- 应用备注
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Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- 抗原
- alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))
- 别名
- Defensin alpha 1 (DEFA1 产品)
- 别名
- DEF1 antibody, DEFA2 antibody, HNP-1 antibody, HP-1 antibody, HP1 antibody, MRS antibody, Defcr antibody, Defcr1 antibody, DEFA1 antibody, Defa antibody, Def antibody, GB19392 antibody, defensin alpha 1 antibody, defensin, alpha 1 antibody, defensin alpha 5 antibody, alpha-defensin 1A antibody, defensin 1 antibody, neutrophil defensin 1 antibody, DEFA1 antibody, Defa1 antibody, Defa5 antibody, MNP1A antibody, Def1 antibody, LOC107973256 antibody
- 背景
- β-Defensins (also designated BD, and HBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. β-defensins are involved in the resistance of epithelial surfaces, such as airway surface fluid, to microbial colonization. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Human β-defensin 1, isolated from the kidney, has a molecular mass of 3.9 kDa. Human β-defensin 1 shares homology with other β-defensins from human blood filtrate and is also present in nanomolar concentrations in human plasma. In addition to the antimicrobial activity of human airway epithelia, β-defensin 1 may play a role in the mucosal defenses of the lung.Synonyms: DEF1, DEFA1, DEFA2, HNP-1, MRS, Neutrophil defensin 1
- 基因ID
- 1667
- NCBI登录号
- NP_001035965
- UniProt
- P59665
- 途径
- Cellular Response to Molecule of Bacterial Origin
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