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alpha Defensin 1 抗体

The 兔 多克隆 anti-alpha Defensin 1 antibody (ABIN498525) specifically detects alpha Defensin 1 in IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN498525
发货至: 中国
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Quick Overview for alpha Defensin 1 抗体 (ABIN498525)

抗原

See all alpha Defensin 1 (DEFA1) 抗体
alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

适用

  • 36
  • 4
  • 3

宿主

  • 23
  • 11
  • 3

克隆类型

  • 34
  • 3
多克隆

标记

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  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This alpha Defensin 1 antibody is un-conjugated

应用范围

  • 22
  • 19
  • 13
  • 6
  • 3
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  • 3
  • 2
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  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Defensin α1 protein. (region surrounding Ser52)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % (by SDS-PAGE)
  • 应用备注

    Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    alpha Defensin 1 (DEFA1) (Defensin, alpha 1 (DEFA1))

    别名

    Defensin alpha 1

    背景

    β-Defensins (also designated BD, and HBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. β-defensins are involved in the resistance of epithelial surfaces, such as airway surface fluid, to microbial colonization. Produced in mucosal epithelia and neutrophils of several species, β-defensins are developmentally regulated. Human β-defensin 1, isolated from the kidney, has a molecular mass of 3.9 kDa. Human β-defensin 1 shares homology with other β-defensins from human blood filtrate and is also present in nanomolar concentrations in human plasma. In addition to the antimicrobial activity of human airway epithelia, β-defensin 1 may play a role in the mucosal defenses of the lung.Synonyms: DEF1, DEFA1, DEFA2, HNP-1, MRS, Neutrophil defensin 1

    基因ID

    1667

    NCBI登录号

    NP_001035965

    UniProt

    P59665

    途径

    Cellular Response to Molecule of Bacterial Origin
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