DEFA4 抗体
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北京 101111
Quick Overview for DEFA4 抗体 (ABIN498518)
抗原
See all DEFA4 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Defensin α4 protein. (region surrounding Asp27)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Defensin, alpha 4, Corticostatin (DEFA4) (AA 23-97) antibody
DEFA4 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 4, Corticostatin (DEFA4) (AA 20-92) antibodyDEFA4 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Defensin, alpha 4, Corticostatin (DEFA4) antibodyDEFA4 适用: 人, 小鼠, 大鼠 IHC, ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))
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别名
- Defensin alpha 4
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背景
- Human neutrophil alpha-defensins (also designated HNPs) are small, cationic, cysteine-rich antimicrobial proteins that play important roles in innate immunity against infectious microbes such as bacteri,a fungi and enveloped viruses. Alpha-defensins are synthesized as inactive precursors and are activated by proteolytic cleavage by MMP-7. Paneth cells in small intestinal crypts secrete the alpha-defensins, which are also termed cryptidins in mice. The cryptidin-4 gene is unique among the Paneth cell alpha defensins in that it is inactive in the duodenum, but expressed at maximal levels in the distal small bowel.Synonyms: DEF4, DEFA4, HNP-4, HP-4, Neutrophil defensin 4
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分子量
- approx. 11 kDa
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基因ID
- 1669
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NCBI登录号
- NP_001916
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UniProt
- P12838
抗原
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