PAX1 抗体
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北京 101111
Quick Overview for PAX1 抗体 (ABIN498514)
抗原
See all PAX1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Pax-1 protein. (region surrounding Thr367)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Paired Box 1 (PAX1) (AA 151-250) antibody
PAX1 适用: 人, 小鼠 ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 1 (PAX1) (AA 318-329) antibodyVerified PAX1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 1 (PAX1) (AA 443-471), (C-Term) antibodyPAX1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB20214 unconjugated
anti-Paired Box 1 (PAX1) (Middle Region) antibodyPAX1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 1 (PAX1) (AA 443-471) antibodyPAX1 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 1 (PAX1) (AA 216-265) antibodyPAX1 适用: 人, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 1 (PAX1) (AA 324-373) antibodyPAX1 适用: 人, 犬, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 1 (PAX1) (Internal Region) antibodyPAX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 1 (PAX1) (AA 163-189), (N-Term) antibodyPAX1 适用: 人 WB 宿主: 兔 Polyclonal RB20213 unconjugated
anti-Paired Box 1 (PAX1) (AA 218-382) antibodyPAX1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- PAX1 (Paired Box 1 (PAX1))
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别名
- PAX1
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背景
- Pax genes contain paired domains with strong homology to genes in Drosophila that are involved in programming early development. Pax-1 is a sequence-specific DNA binding-protein with transcriptional activating properties. The expression pattern of Pax-1 during mouse embryogenesis indicates that it may play an important role in the development of the vertebral column. The autosomal recessive mutation 'undulated' (un) in the mouse exhibits vertebral anomalies along the entire rostrocaudal axis and is associated with a point mutation (G-to-A transition) at position 15 leading to a gly-to-ser replacement in a highly conserved region of the paired box of Pax-1. Pax-1 is required for the normal development of these three skeletal elements: the vertebral column, sternum, and scapula. Mice who are doubly heterozygous for the mutants 'undulated' and 'Patch' have a phenotype reminiscent of an extreme form of spina bifida occulta in humans. The gene which encodes Pax-1 maps to human chromosome 20p11.2.Synonyms: HUP48, Paired box protein Pax-1, Pax-1
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分子量
- approx. 36 kDa
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基因ID
- 5075
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NCBI登录号
- NP_006183
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UniProt
- P15863
抗原
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