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LTA 抗体

The 兔 多克隆 anti-LTA antibody is suitable to detect LTA. It has been validated for WB.
产品编号 ABIN498512
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for LTA 抗体 (ABIN498512)

抗原

See all LTA 抗体
LTA (Lymphotoxin-alpha (LTA))

宿主

  • 67
  • 29
  • 5
  • 1

克隆类型

  • 68
  • 33
  • 1
多克隆

标记

  • 59
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  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
This LTA antibody is un-conjugated

应用范围

  • 67
  • 36
  • 29
  • 24
  • 18
  • 10
  • 8
  • 7
  • 4
  • 3
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  • 2
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  • 1
Western Blotting (WB)
  • 特异性

    This antibody detects endogenous levels of TNF-? protein. (region surrounding His66)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography using epitope-specific immunogen

    纯度

    > 95 % (by SDS-PAGE)
  • 应用备注

    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    LTA (Lymphotoxin-alpha (LTA))

    别名

    TNF-beta / Lymphotoxin-alpha

    物质类

    Chemical

    背景

    Tumor necrosis factor b (TNFb), also known as lymphotoxin, is a pleiotropic cytokine. TNFa, also known as cachectin, is a smaller cytokine that binds to the same receptors, producing a vast array of effects similar to those of TNFb. TNFb and TNFa share 30?% amino acid homology and have similar biological activities. TNFb is produced by activated lymphocytes, including CD4(+) T helper cell type 1 lymphocytes, CD8(+) lymphocytes and certain B lymphoblastoid cell lines. TNFa is produced by several different cell types, including lymphocytes, neutrophils and macrophages. TNFa and TNFb can modulate many immune and inflammatory functions, while having the ability to inhibit tumor growth.Synonyms: LT-alpha, LTA, TNFB, TNFSF1, Tumor necrosis factor ligand superfamily member 1

    分子量

    approx. 22 kDa

    基因ID

    4049

    NCBI登录号

    NP_000586

    UniProt

    P01374

    途径

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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