IL12B 抗体
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北京 101111
Quick Overview for IL12B 抗体 (ABIN498502)
抗原
See all IL12B 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of IL-12B protein. (region surrounding Val277)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Interleukin 12 beta (IL12B) (AA 201-300) antibody
IL12B 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 30-320) antibodyIL12B 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated
anti-Interleukin 12 beta (IL12B) (AA 229-328) antibodyIL12B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Interleukin 12 beta (IL12B) (Internal Region) antibodyVerified IL12B 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (Internal Region) antibodyVerified IL12B 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-328) antibodyIL12B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 23-327) antibodyIL12B 适用: 绵羊 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (AA 264-290), (C-Term) antibodyIL12B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB28444 unconjugated
anti-Interleukin 12 beta (IL12B) (AA 35-302) antibodyIL12B 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 beta (IL12B) (C-Term) antibodyIL12B 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL12B (Interleukin 12 beta (IL12B))
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别名
- Interleukin-12 beta / IL12B
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背景
- The interleukins (ILs) are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. As new cytokines are molecularly characterized, they are assigned an IL number to maintain a standard nomenclature. ILs are secreted by immune cells that regulate a wide range of immune system functions. IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-gamma (IFN-gamma). It also activates production of tumor necrosis factor alpha (TNFalpha) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-gamma. IL-12 also has anti-angiogenic activity since the production of IFN-gamma increases the production of inducible protein-10 (IP-10). IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.Synonyms: CLMF p40, Cytotoxic lymphocyte maturation factor 40 kDa subunit, IL-12 subunit p40, IL-12B, Interleukin-12B, NK cell stimulatory factor chain 2, NKSF2
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分子量
- approx. 44 kDa
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基因ID
- 3593
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NCBI登录号
- NP_002178
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UniProt
- P29460
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途径
- JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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