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IL-20 抗体

IL20 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498487
发货至: 中国
  • 抗原 See all IL-20 (IL20) 抗体
    IL-20 (IL20) (Interleukin 20 (IL20))
    适用
    • 31
    • 16
    • 6
    人, 小鼠
    宿主
    • 32
    • 11
    • 3
    • 1
    克隆类型
    • 36
    • 11
    多克隆
    标记
    • 24
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-20 antibody is un-conjugated
    应用范围
    • 34
    • 13
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of IL-20 protein. (region surrounding Asp61)
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse.
    纯化方法
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product IL20 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    IL-20 (IL20) (Interleukin 20 (IL20))
    别名
    Interleukin-20 / IL20 (IL20 产品)
    别名
    IL-20 antibody, IL10D antibody, ZCYTO10 antibody, Zcyto10 antibody, IL20 antibody, interleukin 20 antibody, IL20 antibody, Il20 antibody
    背景
    The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-lambda. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ralpha and IL-20Rbeta. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ralpha and IL-20Rbeta all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.Synonyms: IL-20, ZCYTO10
    分子量
    approx. 28 kDa
    基因ID
    50604
    NCBI登录号
    NP_061194
    UniProt
    Q9NYY1
    途径
    Protein targeting to Nucleus
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