IL-20 抗体
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北京 101111
Quick Overview for IL-20 抗体 (ABIN498487)
抗原
See all IL-20 (IL20) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of IL-20 protein. (region surrounding Asp61)
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse.
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纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Interleukin 20 (IL20) (AA 67-176) antibody
IL20 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2H8 unconjugated
anti-Interleukin 20 (IL20) (AA 25-176) antibodyIL20 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 (IL20) (AA 25-176) antibodyIL20 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 (IL20) (AA 1-176) antibodyIL20 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 20 (IL20) (AA 1-176) antibodyIL20 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 20 (IL20) (Internal Region) antibodyIL20 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IL-20 (IL20) (Interleukin 20 (IL20))
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别名
- Interleukin-20 / IL20
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背景
- The class II cytokine receptor family includes 12 members, 11 of which combine as various heterodimers to transduce signals across the cellular membrane for 27 cytokines. These cytokines are divided into four structurally related groups: six cytokines of the IL-10 family, 17 type I IFNs, one type II IFN and three IFN-lambda. IL-20 is a member of the IL-10 family of cytokines that has been shown to be upregulated in psoriatic skin. The receptor for IL-20 (IL-20R) exists as a dimer consisting of IL-20Ralpha and IL-20Rbeta. IL-20R also functions as a receptor for IL-19, IL-24 and IL-26. It is highly expressed in skin, brain and testis. IL-20, IL-20Ralpha and IL-20Rbeta all have higher expression levels in psoriatic lesional (LS) skin than in nonlesional (NL) skin, suggesting a role for these proteins as potential therapeutic targets. IL-20 can induce signal transducer and activator of transcription (Stat) activation through IL-20R.Synonyms: IL-20, ZCYTO10
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分子量
- approx. 28 kDa
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基因ID
- 50604
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NCBI登录号
- NP_061194
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UniProt
- Q9NYY1
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途径
- Protein targeting to Nucleus
抗原
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