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FASTK 抗体

FASTK 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498486
发货至: 中国
  • 抗原 See all FASTK 抗体
    FASTK (Fas-Activated serine/threonine Kinase (FASTK))
    适用
    • 39
    • 28
    • 7
    • 2
    • 2
    人, 小鼠, 大鼠
    宿主
    • 50
    • 3
    克隆类型
    • 51
    • 2
    多克隆
    标记
    • 31
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FASTK antibody is un-conjugated
    应用范围
    • 42
    • 28
    • 10
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    This antibody detects endogenous levels of FAST protein. (region surrounding Arg410)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product FASTK Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    PBS, pH ~7.2, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    FASTK (Fas-Activated serine/threonine Kinase (FASTK))
    别名
    FAST Kinase (FASTK 产品)
    别名
    FASTK antibody, DKFZp469E0832 antibody, FAST antibody, 0610011K02Rik antibody, 610011K02Rik antibody, Fas activated serine/threonine kinase antibody, Fas-activated serine/threonine kinase antibody, FASTK antibody, Fastk antibody
    背景
    The Human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states. FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4. Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues. FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGβ and activin, indicating that these FAST proteins mediate TFGβ induced signal transduction.Synonyms: FASTK, Fas-activated serine/threonine kinase
    分子量
    approx. 60 kDa
    基因ID
    10922
    NCBI登录号
    NP_006703
    UniProt
    Q14296
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