FASTK 抗体
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北京 101111
Quick Overview for FASTK 抗体 (ABIN498486)
抗原
See all FASTK 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of FAST protein. (region surrounding Arg410)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Fas-Activated serine/threonine Kinase (FASTK) (C-Term) antibody
FASTK 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) (AA 67-154) antibodyFASTK 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B7 unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) (AA 360-549) antibodyFASTK 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) (AA 395-424), (C-Term) antibodyFASTK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB09593 unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) (AA 519-549), (C-Term) antibodyFASTK 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB5302 unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) (Internal Region) antibodyFASTK 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) (AA 67-154) antibodyFASTK 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) (AA 1-549) antibodyFASTK 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) antibodyFASTK 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas-Activated serine/threonine Kinase (FASTK) (AA 394-424), (C-Term) antibodyFASTK 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS, pH ~7.2, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- FASTK (Fas-Activated serine/threonine Kinase (FASTK))
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别名
- FAST Kinase
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背景
- The Human homolog FAST-1 and the corresponding mouse homolog, designated FAST-2, share significant sequence homology with xFAST-1, including a conserved N-terminal forkhead domain that consists of 110 amino acid residues and is essential for binding DNA and regulating transcription in embryogenesis, in tumorigenesis and in the maintenance of differentiated cell states. FAST-1 and FAST-2 also contain a distinct C-terminal Smad interaction domain that is required for the association with various Smad proteins, including Smad2, Smad3 and Smad4. Expression of FAST-1 and FAST-2 is predominantly observed during early development, with lower levels detected in adult tissues. FAST-1 and FAST-2 mediated DNA binding is attenuated by both TFGβ and activin, indicating that these FAST proteins mediate TFGβ induced signal transduction.Synonyms: FASTK, Fas-activated serine/threonine kinase
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分子量
- approx. 60 kDa
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基因ID
- 10922
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NCBI登录号
- NP_006703
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UniProt
- Q14296
抗原
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