Cnpase 抗体
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北京 101111
Quick Overview for Cnpase 抗体 (ABIN498484)
抗原
See all Cnpase (CNP) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of CNPase protein. (region surrounding Ala108)
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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应用备注
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))
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别名
- CNPase
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背景
- CNPase (2',3'-Cyclic Nucleotide 3'-Phosphodiesterase) exists in two forms: 46 kDa (CNP1) and 48 kDa (CNP2). It is expressed at high levels by oligodendrocytes in the central nervous system and by Schwann cells in the peripheral nervous system and is virtual absent in other cell types. CNPase activity is decreased in demyelinating diseases such as multiple sclerosis. CNPase gene is localized to chromosome 17q21, very near the BRCA 1 familial breast cancer gene.Synonyms: 2', 3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, CNP1, Oligodendrocyte Marker
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分子量
- approx. 48 kDa
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基因ID
- 1267
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NCBI登录号
- NP_149124
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UniProt
- P09543
抗原
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