Leptin Receptor 抗体
Our Local Distributor
北京 101111
Quick Overview for Leptin Receptor 抗体 (ABIN498483)
抗原
See all Leptin Receptor (LEPR) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of Ob-R protein. (region surrounding Leu662)
-
交叉反应 （详细）
- Species reactivity (tested):Human.
-
纯化方法
- Affinity chromatography
-
纯度
- > 95 % by SDS-PAGE
-
-
anti-Leptin Receptor (LEPR) (AA 901-1000) antibody
LEPR 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 22-203) antibodyLEPR 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 310-539) antibodyLEPR 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 238-375) antibodyLEPR 适用: 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (Internal Region) antibodyVerified LEPR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 777-791), (Extracellular) antibodyLEPR 适用: 小鼠 WB, IHC, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) antibodyLEPR 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 23-52) antibodyLEPR 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 501-600) antibodyLEPR 适用: 人, 小鼠, 大鼠 WB, FACS, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Leptin Receptor (LEPR) (AA 23-52), (N-Term) antibodyLEPR 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB02053 unconjugated
-
-
应用备注
-
Western Blot: 1/500. Immunohistochemistr: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1,0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Leptin Receptor (LEPR)
-
别名
- CD295 / Leptin Receptor
-
背景
- Although there is substantial evidence that body weight is physiologically regulated, the molecular basis of obesity is unknown. Five single-gene mutations in mice that result in an obese phenotype have been identified. The first such recessive obesity mutation, the obese mutation (Ob), was identified in 1950. Mutation of Ob results in profound obesity and type II diabetes as part of a syndrome that resembles morbid obesity in humans. It has been postulated that the Ob gene product may function as a component of a signaling pathway in adipose tissue that functions to regulate body fat depot size. The cloning and sequence analysis of the mouse Ob gene and its human homolog has recently been described. Ob encodes an adipose tissue-specific mRNA with a highly conserved 167 amino acid open reading frame. The predicted amino acid sequence is 84 % identical between human and mouse and has the features of a secreted protein. A nonsense mutation in codon 105 has been found in the original congenic C57BL/6J Ob/Ob mouse strain. The Ob gene encodes the protein leptin.Synonyms: DB, HuB219, LEP-R, LEPR, OB receptor, OB-R, OBR
-
分子量
- approx. 150 kDa
-
基因ID
- 3953
-
NCBI登录号
- NP_001003679
-
UniProt
- P48357
-
途径
- JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
抗原
-
