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BMP6 抗体

This 兔 多克隆 antibody specifically detects BMP6 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN498475
发货至: 中国
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中国
北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for BMP6 抗体 (ABIN498475)

抗原

See all BMP6 抗体
BMP6 (Bone Morphogenetic Protein 6 (BMP6))

适用

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宿主

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克隆类型

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多克隆

标记

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This BMP6 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of BMP-6 protein. (region surrounding Ala152)

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BMP6 (Bone Morphogenetic Protein 6 (BMP6))

    别名

    BMP6

    背景

    Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.Synonyms: BMP-6, Bone morphogenetic protein 6, VGR, VGR1

    分子量

    approx. 57 kDa

    基因ID

    654

    NCBI登录号

    NP_001709

    UniProt

    P22004

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
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