BMP6 抗体
Our Local Distributor
北京 101111
Quick Overview for BMP6 抗体 (ABIN498475)
抗原
See all BMP6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of BMP-6 protein. (region surrounding Ala152)
-
交叉反应 (详细)
- Species reactivity (tested):Human.
-
纯化方法
- Affinity chromatography
-
纯度
- > 95 % by SDS-PAGE
-
-
-
-
应用备注
-
Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1,0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- BMP6 (Bone Morphogenetic Protein 6 (BMP6))
-
别名
- BMP6
-
背景
- Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.Synonyms: BMP-6, Bone morphogenetic protein 6, VGR, VGR1
-
分子量
- approx. 57 kDa
-
基因ID
- 654
-
NCBI登录号
- NP_001709
-
UniProt
- P22004
-
途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process
抗原
-