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Adrenomedullin 抗体

This 兔 多克隆 antibody specifically detects Adrenomedullin in IHC (p). It exhibits reactivity toward 人, 大鼠 和 小鼠.
产品编号 ABIN498472
发货至: 中国
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Quick Overview for Adrenomedullin 抗体 (ABIN498472)

抗原

See all Adrenomedullin (ADM) 抗体
Adrenomedullin (ADM)

适用

  • 57
  • 47
  • 15
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  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 96
  • 15
  • 2
  • 1
  • 1

克隆类型

  • 99
  • 16
多克隆

标记

  • 53
  • 18
  • 10
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Adrenomedullin antibody is un-conjugated

应用范围

  • 54
  • 36
  • 34
  • 26
  • 26
  • 15
  • 14
  • 8
  • 8
  • 7
  • 6
  • 4
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  • 3
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of ADM protein. (region surrounding asn100)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - -1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Adrenomedullin (ADM)

    物质类

    Hormone

    背景

    Adrenomedullin (ADM), a vasodilator produced by most contractile cells, is characterized by persistent hypotensive activity. ADM is involved in the regulation of fluid and electrolyte homeostasis and in the maintenance of cardiovascular functioning. In hypertensive patients, the level of ADM in plasma is upregulated. Natriuresis is a common systemic manifestation of aneurysmal subarachnoid hemorrhage. ADM has strong natriuretic actions. ADM-induced natriuresis is caused by an increase in glomerular filtration rate and a decrease in distal tubular sodium reabsorption. ADM is present both in the periphery and brain, and can exert central effects such as decreasing food ingestion.

    基因ID

    133

    NCBI登录号

    NP_001115

    UniProt

    P35318

    途径

    Hormone Transport, Hormone Activity, C21-Steroid Hormone Metabolic Process, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Tube Formation
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