GZMH 抗体
Quick Overview for GZMH 抗体 (ABIN498458)
抗原
See all GZMH 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Granzyme H protein. (region surrounding Gly75)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 20-246) antibody
GZMH 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 1-246) antibodyGZMH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) antibodyGZMH 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 19-246) antibodyGZMH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (N-Term) antibodyGZMH 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (Center) antibodyGZMH 适用: 人 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 19-52) antibodyGZMH 适用: 人 WB 宿主: 兔 Polyclonal RB53067 unconjugated
anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (AA 51-100) antibodyGZMH 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH) (N-Term) antibodyGZMH 适用: 人, 小鼠, 大鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))
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别名
- Granzyme H (GZMH)
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背景
- The granzyme family of proteins belong to the larger peptidase S1 family. Granzyme A and granzyme B are serine proteases that facilitate apoptotic signaling in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Within the granules of activated CTLs, granzyme A and granzyme B are processed and converted to their active forms by the lysosomal cysteine protease cathepsin C. Once cleaved, these active proteases target distinct substrates for proteolysis and, thereby, mediate apoptosis through two different pathways. Granzyme H, also designated cytotoxic T-lymphocyte proteinase, cathepsin G-like 2 (CTSGL2) or cytotoxic serine protease C (CSP-C), contains one peptidase S1 domain. Granzyme H localizes to cytoplasmic granules of cytolytic T-lymphocytes and is important for target cell lysis in cell-mediated immune responsesSynonyms: CCP-X, CGL2, CSP-C, CTSGL2, Cathepsin G-like 2, Cytotoxic T-lymphocyte proteinase, Cytotoxic serine protease C
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分子量
- approx. 23 kDa
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基因ID
- 2999
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NCBI登录号
- NP_219491
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UniProt
- P20718
抗原
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