LGALS7 抗体
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北京 101111
Quick Overview for LGALS7 抗体 (ABIN498454)
抗原
See all LGALS7 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Bax protein. (region surrounding Cys62)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Galectin 7 (LGALS7) (AA 1-136) antibody
LGALS7 适用: 人 WB 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Galectin 7 (LGALS7) (AA 31-100) antibodyLGALS7 适用: 大鼠 WB, ELISA, ICC, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Galectin 7 (LGALS7) (AA 1-136) antibodyLGALS7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Galectin 7 (LGALS7) (AA 1-136) antibodyLGALS7 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6B5 unconjugated
anti-Galectin 7 (LGALS7) antibodyLGALS7 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Galectin 7 (LGALS7) (AA 54-82) antibodyLGALS7 适用: 人 WB 宿主: 兔 Polyclonal RB31765 unconjugated
anti-Galectin 7 (LGALS7) (AA 1-128) antibodyLGALS7 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Galectin 7 (LGALS7) (AA 2-136) antibodyLGALS7 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Galectin 7 (LGALS7) antibody (FITC)LGALS7 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal FITC
anti-Galectin 7 (LGALS7) antibody (HRP)LGALS7 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal HRP
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- LGALS7 (Galectin 7 (LGALS7))
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别名
- Galectin-7
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背景
- Bcl2 family is a key regulator of apoptosis that functions to either inhibit or promote cell death. Over-expression of members such as Bcl2 and BclxL inhibit the apoptotic process. The Bcl2 family members are also characterized by dimerizing to further modulate apoptosis. Bag1, for example, has been found to form a heterodimer with Bcl2 resulting in the enhancement of the anti-apoptotic effect of Bcl2. Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis. Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells. Bax targets mitochondrial membranes, inducing mitochondrial damage and cell death in a caspase-independent manner. Bad plays a critical role in the Bax-mediated apoptosis pathway by dimerizing with BclxL, causing the displacment of Bax. The displacement of Bax allows apoptosis to proceed. BclxS, a shorter version of BclxL (lacking amino acids 126-188), apparently utilizes a different pathway than Bax to induce cell death.Synonyms: Gal-7, HKL-14, LGALS7, LGALS7B, PI7, PIG1, p53-induced gene 1 protein
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分子量
- approx. 24 kDa
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基因ID
- 3963
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NCBI登录号
- NP_001035972
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UniProt
- P47929
抗原
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