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LGALS7 抗体

LGALS7 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498454
发货至: 中国
  • 抗原 See all LGALS7 抗体
    LGALS7 (Galectin 7 (LGALS7))
    适用
    • 57
    • 36
    • 27
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 82
    • 12
    • 1
    克隆类型
    • 74
    • 21
    多克隆
    标记
    • 30
    • 16
    • 13
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This LGALS7 antibody is un-conjugated
    应用范围
    • 58
    • 29
    • 24
    • 14
    • 14
    • 13
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Bax protein. (region surrounding Cys62)
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product LGALS7 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    LGALS7 (Galectin 7 (LGALS7))
    别名
    Galectin-7 (LGALS7 产品)
    别名
    GAL7 antibody, LGALS7A antibody, Galectin-7 antibody, Pig1 antibody, LGALS7 antibody, galectin-7 antibody, galectin 7 antibody, lectin, galactose binding, soluble 7 antibody, galectin-7 antibody, LGALS7 antibody, Lgals7 antibody, LOC101112249 antibody
    背景
    Bcl2 family is a key regulator of apoptosis that functions to either inhibit or promote cell death. Over-expression of members such as Bcl2 and BclxL inhibit the apoptotic process. The Bcl2 family members are also characterized by dimerizing to further modulate apoptosis. Bag1, for example, has been found to form a heterodimer with Bcl2 resulting in the enhancement of the anti-apoptotic effect of Bcl2. Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis. Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells. Bax targets mitochondrial membranes, inducing mitochondrial damage and cell death in a caspase-independent manner. Bad plays a critical role in the Bax-mediated apoptosis pathway by dimerizing with BclxL, causing the displacment of Bax. The displacement of Bax allows apoptosis to proceed. BclxS, a shorter version of BclxL (lacking amino acids 126-188), apparently utilizes a different pathway than Bax to induce cell death.Synonyms: Gal-7, HKL-14, LGALS7, LGALS7B, PI7, PIG1, p53-induced gene 1 protein
    分子量
    approx. 24 kDa
    基因ID
    3963
    NCBI登录号
    NP_001035972
    UniProt
    P47929
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