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LAMa4 抗体

The 兔 多克隆 anti-LAMa4 antibody (ABIN498447) specifically detects LAMa4 in WB, IF 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN498447
发货至: 中国
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Quick Overview for LAMa4 抗体 (ABIN498447)

抗原

See all LAMa4 抗体
LAMa4 (Laminin, alpha 4 (LAMa4))

适用

  • 52
  • 12
  • 1
人, 小鼠

宿主

  • 52
  • 7
  • 1

克隆类型

  • 55
  • 5
多克隆

标记

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  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
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This LAMa4 antibody is un-conjugated

应用范围

  • 34
  • 17
  • 13
  • 13
  • 11
  • 8
  • 8
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  • 1
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of Laminin alpha-4 protein. (region surrounding Ala511)

    交叉反应 (详细)

    Species reactivity (tested):Human and Mouse.

    纯化方法

    Affinity Chromatography using epitope-specific immunogen.
  • 应用备注

    Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    LAMa4 (Laminin, alpha 4 (LAMa4))

    别名

    Laminin alpha 4

    背景

    Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cellassociated extracellular matrices (ECMs)) are polymers of laminins with stabilizing type IV collagen networks, nidogen, and several proteoglycans.Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of α, β, and γ chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan, and cognate laminin receptors. The human laminin α-4 gene maps to chromosome 6q21 and is expressed in adult heart, lung, ovary, small and large intestines, liver, and placenta.Synonyms: LAMA4, Laminin subunit alpha-4

    分子量

    approx. 203 kDa

    基因ID

    3910

    NCBI登录号

    NP_001098676

    UniProt

    Q16363

    途径

    Brown Fat Cell Differentiation
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