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ADD2 抗体

The 兔 多克隆 anti-ADD2 antibody is suitable to detect ADD2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 IF.
产品编号 ABIN498443
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ADD2 抗体 (ABIN498443)

抗原

See all ADD2 抗体
ADD2 (Adducin 2 (Beta) (ADD2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ADD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 特异性

    This antibody detects endogenous levels of Adducin beta protein.(region surrounding Glu497)

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.2, 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ADD2 (Adducin 2 (Beta) (ADD2))

    别名

    beta-Adducin (ADD2)

    背景

    Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and adducins are central in the cortical actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta. Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans, and spleen in mice.Synonyms: ADDB, Adducin 2, Erythrocyte adducin subunit beta

    分子量

    approx. 81 kDa

    基因ID

    119

    NCBI登录号

    NP_001608

    UniProt

    P35612

    途径

    Regulation of Actin Filament Polymerization
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