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AKAP1 抗体

AKAP1 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498433
发货至: 中国
  • 抗原 See all AKAP1 抗体
    AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
    适用
    • 28
    • 2
    • 1
    宿主
    • 25
    • 3
    克隆类型
    • 28
    多克隆
    标记
    • 21
    • 1
    • 1
    • 1
    • 1
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    This AKAP1 antibody is un-conjugated
    应用范围
    • 18
    • 11
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    • 8
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    • 2
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of AKAP149 protein. (region surrounding asn306)
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity-Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product AKAP1 Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
    别名
    AKAP1 (AKAP1 产品)
    别名
    AKAP1 antibody, akap1 antibody, fa08b04 antibody, wu:fa08b04 antibody, AKAP antibody, AKAP121 antibody, AKAP149 antibody, AKAP84 antibody, D-AKAP1 antibody, PPP1R43 antibody, PRKA1 antibody, SAKAP84 antibody, TDRD17 antibody, Akap antibody, C76494 antibody, C81186 antibody, DAKAP1 antibody, S-AKAP84 antibody, Akap84 antibody, A-kinase anchoring protein 1 antibody, A kinase (PRKA) anchor protein 1b antibody, A kinase (PRKA) anchor protein 1 antibody, AKAP1 antibody, akap1b antibody, akap1 antibody, Akap1 antibody
    背景
    The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. This family of proteins has been designated A-kinase anchoring proteins (AKAP). Members of this family, including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, and the DNA binding AKAP 95, display differential tissue specificity and localization. Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), which are a network of proteins located on the internal surfaces of excitatory synapses.Synonyms: A kinase anchor protein 1 mitochondrial, A-kinase anchor protein 149 kDa, AKAP-1, AKAP149, Dual specificity A-kinase-anchoring protein 1, PRKA1, Protein kinase A-anchoring protein 1, Spermatid A-kinase anchor protein 84
    分子量
    approx. 90 kDa
    基因ID
    8165
    NCBI登录号
    NP_003479
    UniProt
    Q92667
    途径
    Synaptic Membrane
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