AKAP1 抗体
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Quick Overview for AKAP1 抗体 (ABIN498433)
抗原
See all AKAP1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of AKAP149 protein. (region surrounding asn306)
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity-Chromatography using epitope-specific immunogen
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anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (Internal Region) antibody
AKAP1 适用: 人, 小鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 375-425) antibodyAKAP1 适用: 人 IHC, IF (p) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 806-903) antibodyAKAP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 281-330) antibodyAKAP1 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (Center) antibodyAKAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 1-903) antibodyAKAP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 541-571) antibodyAKAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 375-425) antibodyAKAP1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (C-Term) antibodyAKAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
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别名
- AKAP1
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背景
- The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. This family of proteins has been designated A-kinase anchoring proteins (AKAP). Members of this family, including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, and the DNA binding AKAP 95, display differential tissue specificity and localization. Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), which are a network of proteins located on the internal surfaces of excitatory synapses.Synonyms: A kinase anchor protein 1 mitochondrial, A-kinase anchor protein 149 kDa, AKAP-1, AKAP149, Dual specificity A-kinase-anchoring protein 1, PRKA1, Protein kinase A-anchoring protein 1, Spermatid A-kinase anchor protein 84
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分子量
- approx. 90 kDa
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基因ID
- 8165
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NCBI登录号
- NP_003479
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UniProt
- Q92667
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途径
- Synaptic Membrane
抗原
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