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DGKQ 抗体

The 兔 多克隆 anti-DGKQ antibody (ABIN498426) specifically detects DGKQ in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN498426
发货至: 中国
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Quick Overview for DGKQ 抗体 (ABIN498426)

抗原

See all DGKQ 抗体
DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))

适用

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宿主

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克隆类型

  • 32
多克隆

标记

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This DGKQ antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody reacts to DGKQ.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))

    别名

    DAG Kinase theta

    背景

    Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. The accumulation of DAG in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I-Type V. DGK-theta is a Type V DGK, and localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12 and HeLa. Nuclear DGK-theta co-localizes with phosphatidylinositol 4,5-bisphosphate (PIP(2)). DGK-theta is the isoform responsive to alpha-Thrombin stimulation.Synonyms: DAGK4, DGK-theta, DGKQ, Diacylglycerol kinase theta, Diglyceride kinase theta

    分子量

    approx. 101 kDa

    基因ID

    1609

    NCBI登录号

    NP_001338

    UniProt

    P52824
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