DGKQ 抗体
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北京 101111
Quick Overview for DGKQ 抗体 (ABIN498426)
抗原
See all DGKQ 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody reacts to DGKQ.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))
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别名
- DAG Kinase theta
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背景
- Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. The accumulation of DAG in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I-Type V. DGK-theta is a Type V DGK, and localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12 and HeLa. Nuclear DGK-theta co-localizes with phosphatidylinositol 4,5-bisphosphate (PIP(2)). DGK-theta is the isoform responsive to alpha-Thrombin stimulation.Synonyms: DAGK4, DGK-theta, DGKQ, Diacylglycerol kinase theta, Diglyceride kinase theta
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分子量
- approx. 101 kDa
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基因ID
- 1609
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NCBI登录号
- NP_001338
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UniProt
- P52824
抗原
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