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DGKQ 抗体

DGKQ 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498426
发货至: 中国
  • 抗原 See all DGKQ 抗体
    DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))
    适用
    • 29
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    宿主
    • 28
    • 1
    克隆类型
    • 29
    多克隆
    标记
    • 12
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    This DGKQ antibody is un-conjugated
    应用范围
    • 17
    • 16
    • 9
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody reacts to DGKQ.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography
    纯度
    > 95 % by SDS-PAGE
    Top Product
    Discover our top product DGKQ Primary Antibody
  • 应用备注
    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1,0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DGKQ (Diacylglycerol Kinase, theta 110kDa (DGKQ))
    别名
    DAG Kinase theta (DGKQ 产品)
    别名
    DAGK antibody, DAGK4 antibody, DAGK7 antibody, 110kDa antibody, Dagk4 antibody, Dgkd antibody, diacylglycerol kinase theta antibody, diacylglycerol kinase, theta antibody, diacylglycerol kinase, theta, putative antibody, DGKQ antibody, Dgkq antibody, Smp_163080 antibody, Tsp_13406 antibody
    背景
    Diacylglycerol (DAG) is a fundamental lipid second messenger that is produced in the nucleus. The accumulation of DAG in the nucleus is important for the regulation of cell growth and differentiation. Diacylglycerol kinases (DGKs) convert DAG to phosphatidic acid, thereby terminating diacylglycerol signaling, which results in the reduction of protein kinase C activity and cell cycle progression of T lymphocytes. Diacylglycerol kinases are divided into five subtypes, Type I-Type V. DGK-theta is a Type V DGK, and localizes mainly to the nucleus of various cell lines, such as MDA-MB-453, MCF-7, PC12 and HeLa. Nuclear DGK-theta co-localizes with phosphatidylinositol 4,5-bisphosphate (PIP(2)). DGK-theta is the isoform responsive to alpha-Thrombin stimulation.Synonyms: DAGK4, DGK-theta, DGKQ, Diacylglycerol kinase theta, Diglyceride kinase theta
    分子量
    approx. 101 kDa
    基因ID
    1609
    NCBI登录号
    NP_001338
    UniProt
    P52824
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