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RBM5 抗体

The 兔 多克隆 anti-RBM5 antibody (ABIN498423) specifically detects RBM5 in WB 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN498423
发货至: 中国
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Quick Overview for RBM5 抗体 (ABIN498423)

抗原

See all RBM5 抗体
RBM5 (RNA Binding Motif Protein 5 (RBM5))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This RBM5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of LUCA15 protein. (region surrounding asn261)

    交叉反应 (详细)

    Species reactivity (expected):Mouse.
    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography

    纯度

    > 95 % by SDS-PAGE
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1,0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RBM5 (RNA Binding Motif Protein 5 (RBM5))

    别名

    RBM5 / LUCA15

    背景

    DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similiar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.Synonyms: NY-REN-9, Putative tumor suppressor LUCA15, RNA-binding motif protein 5, RNA-binding protein 5, Renal carcinoma antigen NY-REN-9

    分子量

    approx. 92 kDa

    基因ID

    10181

    NCBI登录号

    NP_005769

    UniProt

    P52756

    途径

    Ribonucleoprotein Complex Subunit Organization
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