Cyclin O 抗体
This anti-Cyclin O antibody is a 兔 多克隆 antibody detecting Cyclin O in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
Quick Overview for Cyclin O 抗体 (ABIN498417)
抗原
See all Cyclin O (CCNO) 抗体
Cyclin O (CCNO)
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This Cyclin O antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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特异性
- This antibody detects endogenous levels of UDG protein. (region surrounding His221)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography
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纯度
- > 95 % by SDS-PAGE
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anti-Cyclin O (CCNO) (AA 1-257) antibody
CCNO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin O (CCNO) (AA 1-350) antibodyCCNO 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Cyclin O (CCNO)
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别名
- Uracil-DNA Glycosylase 2 / Cyclin-O
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背景
- The human UNG-gene encodes nuclear (UNG2) and mitochondrial (UNG1) forms of uracil-DNA glycosylase using differentially regulated promoters, PA and PB, and alternative splicing to produce two proteins with unique N-terminal sorting sequences. Uracil in DNA may result from deamination of cytosine which can give rise to transition mutations. Uracil-DNA glycosylase is the DNA repair enzyme responsible for the removal of uracil from DNA. This is probably a biologically important function in the prevention of mutagenesis resulting from cytosine deamination. UNG2 removes misincorporated dUMP residues.Synonyms: CCNO, Cyclin-like uracil-DNA glycosylase, UDG2, UNG2
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分子量
- approx. 35 kDa
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基因ID
- 10309
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NCBI登录号
- NP_066970
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UniProt
- P22674
抗原
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